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Janos L Tanyi on Muck Rack

Janos L Tanyi

As seen in: Nature, MDPI, Science Magazine, Cell Reports, Cell Press, Cell Reports Medicine, Future Medicine, OncLive
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Articles

Clinical and molecular dissection of CAR T cell resistance in pancreatic cancer

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By M. Angela Aznar, Julie Barber-Rotenberg, Sangya Agarwal, Wesley Wilson, Alex Watts, Zhen Zhang, Donna Gonzales, Greg Donahue, Wei-Ting Hwang, Austin K. Rennels, Shunichiro Kuramitsu, Hua Huang, Karl Glastad, Katherine Alexander, Gabriela Plesa, Emily Dowd, Andrea M. Brennan, Donald L. Siegel, Janos L Tanyi, Andrew R. Haas, Drew Torigian, Gregory Nadolski, Vanessa Gonzalez, Vanessa González, Elizabeth O. Hexner, Joseph A Fraietta, Julie K. Jadlowsky, Regina Young Verified, Shelley Berger, Carl June, Mark O’Hara
| Cell Reports Medicine Verified
Keywords CAR T cells clinical trial pancreatic cancer T cell dysfunction immunotherapy T cell exhaustion single-cell RNA-seq cancer ID3 SOX4 Introduction Combination chemotherapy is the standard of care for metastatic pancreatic ductal adenocarcinoma (PDAC), but the overall benefit is marginal, and PDAC remains one of the most lethal malignancies.1,2,3 Furthermore, despite the success of immune checkpoint blockade4,5,6 and chimeric antigen receptor (CAR) T cell therapy7,8 in various other...
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CAR-T Cell Therapy in Ovarian Cancer: Where Are We Now?

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By Dimitrios Nasioudis, Erin M. George, Janos L Tanyi, Clare Cutri-French
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Controversies in the Staging of Patients with Locally Advanced Cervical Cancer

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By Dimitrios Nasioudis, Janos L Tanyi, Erin M. George
| MDPI
Abstract : Approximately 10–25% of patients with locally advanced cervical cancer harbor metastases to the para-aortic lymph nodes. Staging of patients with locally advanced cervical cancer can be performed with imaging techniques, such as PET-CT; however, false negative rates can be as high as 20%, especially for patients with pelvic lymph node metastases.
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