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Jessica Lam

As seen in: Nature, Daily Express, ACS Publications, BioRxiv, Cell Press, JD Supra, Lexology, Mondaq, The Varsity, Blogarama and

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Jessica Lam’s Journalist Portfolio

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Slay This Halloween With These Awesome Headpieces

Slay This Halloween With These Awesome Headpieces

How to dress for Halloween when you CBA. Halloween is right around the corner and the conversation of what co…

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This Girl Accidentally Started A Trend With A Shoelace And Became An Internet Legend

This Girl Accidentally Started A Trend With A Shoelace And Became An Internet Legend

Meet your new must-have accessory. The 90's choker trend is making a comeback! You've probably seen them on t…

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Missguided Just Launched A Make Up Line & It's Kawaii AF

Missguided Just Launched A Make Up Line & It's Kawaii AF

Introducing the 'Too Legit Contour Kit'... UK clothing brand, Missguided has created their very first Makeup …

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QUIZ: How Much Do You Love Autumn, Really?

QUIZ: How Much Do You Love Autumn, Really?

Autumn FTW It's that time of year where the leaves fall, the air is crisp and the days are shorter. How much …

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WATCH: Shocking moment man is held down after trying to 'sexually assault' girl on bus

WATCH: Shocking moment man is held down after trying to 'sexually assault' girl on bus

Moise Morancy, a rap artist and actor, confronted a man who he claimed was sexually assaulting a girl on a bu…

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5 Artist Comebacks We Can't Wait For in 2019 - Vinyl Collector Official Blog

5 Artist Comebacks We Can't Wait For in 2019 - Vinyl Collector Official Blog

If 2019 had a nickname, it would be 'The Comeback Kid', as a huge number of artists are making a comeback to …

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Articles

Computer Science > Machine Learning

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By Marian Schneider, Jessica Lam, Martin Wertich
| arxiv.org
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Single-stranded DNA-binding proteins are essential components of the architectural LDB1 protein complex

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By Xiaokang Wang, Nicholas Aboreden, Ying Cai, Jessica Lam, Kate A. Henderson, Jiaqi Xiang, Belinda Giardine, Ross C. Hardison, Cheryl A. Keller, Stephen Brandt, Gerd A. Blobel, Lalitha Nagarajan
| Cell Press Verified
Keywords LDB1 single-stranded DNA-binding protein SSBP3 SSBP2 SSBP4 chromatin looping enhancer-promoter interaction transcription Get full text access Log in, subscribe or purchase for full access. References 1. Furlong, E.E.M. ∙ Levine, M. Developmental enhancers and chromosome topology Science. 2018; 361:1341-1345 2. Zheng, H. ∙ Xie, W. The role of 3D genome organization in development and cell differentiation Nat. Rev. Mol. Cell Biol. 2019; 20:535-550 3. Dekker, J. ∙ Misteli, T.
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Single-stranded DNA binding proteins are essential components of the architectural LDB1 protein complex

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By Xiaokang Wang, Nicholas Aboreden, Ying Cai, Jessica Lam
| BioRxiv
Abstract Transcriptional enhancers are brought into proximity with promoters via chromatin looping. The architectural transcription cofactor LDB1 facilitates spatial connectivity among enhancers and promoters but whether this occurs through simple dimerization or requires partner molecules is unknown. Here we investigated single-stranded DNA binding proteins (SSBPs), known LDB1 interactors, in regulating LDB1-mediated chromatin looping and transcription.
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