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Ji-Heui Seo on Muck Rack

Ji-Heui Seo

As seen in: Nature, BioRxiv, Cell Reports, Cell Press, Cell Reports Medicine, Molecular Cancer Research
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Articles

Reconstructing protein interactions at enhancer-promoter regions in prostate cancer

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By Alexandros Armaos, François Serra, Iker Núñez-Carpintero, Ji-Heui Seo
| BioRxiv
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A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypes

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By Sally Mortlock, Pik Fang Kho, Paul Pharoah, Ji-Heui Seo
| Cell Reports Medicine Verified
Table 3Number of significant SNPs and genomic loci identified in the EOC histotype and endometriosis cross-trait meta-analyses LMP, low malignant potential.
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Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer

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By Sylvan C. Baca, David Y. Takeda, Ji-Heui Seo, Justin H. Hwang
| Nature Verified
Abstract Lineage plasticity, the ability of a cell to alter its identity, is an increasingly common mechanism of adaptive resistance to targeted therapy in cancer. An archetypal example is the development of neuroendocrine prostate cancer (NEPC) after treatment of prostate adenocarcinoma (PRAD) with inhibitors of androgen signaling. NEPC is an aggressive variant of prostate cancer that aberrantly expresses genes characteristic of neuroendocrine (NE) tissues and no longer depends on androgens.
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