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Jianxing Yin on Muck Rack

Jianxing Yin

As seen in: Science Magazine, Cell Press, Texas Medical Center
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Articles

METTL3-Mediated m6A Modification of LINC00839 Maintains Glioma Stem Cells and Radiation Resistance by Activating Wnt/β-Catenin Signaling

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By Jianxing Yin
| Texas Medical Center
Abstract Long noncoding RNAs (lncRNAs) are involved in glioma initiation and progression. Glioma stem cells (GSCs) are essential for tumor initiation, maintenance, and therapeutic resistance. However, the biological functions and underlying mechanisms of lncRNAs in GSCs remain poorly understood. Here, we identified that LINC00839 was overexpressed in GSCs. A high level of LINC00839 was associated with GBM progression and radiation resistance.
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Erratum for the Research Article “Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers,” by C. Sun et al.

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By Emmeran Le Moal, Michael McPherson, Jianxing Yin
| Science Magazine Verified
The Research Article “Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers,” by C. Sun et al. contained errors in Figs. 6B and 8E and in the caption for Fig. 6H. In Fig. 6B, the Western blot for FOXO3a mistakenly showed the blot for BIM overexpression. The Fig. 6H caption incorrectly listed the drug concentrations used for HOC1 and HOC7 cells. In Fig.
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An anti-TNF-glucocorticoid receptor modulator antibody-drug conjugate is efficacious against immune-mediated inflammatory diseases

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By Emmeran Le Moal, Michael McPherson, Jianxing Yin, Adrian D. Hobson
| Science Magazine Verified
Research Article INFLAMMATORY DISEASES Michael J. McPherson https://orcid.org/0000-0001-6344-4600 michael.mcpherson@abbvie.com, Adrian D. Hobson https://orcid.org/0000-0003-3948-0577, [...] , Axel Hernandez Jr., Christopher C. Marvin https://orcid.org/0000-0003-4984-8435, [...] , Wendy Waegell, Christian Goess https://orcid.org/0000-0002-5873-9305, Jason Z. Oh https://orcid.org/0000-0001-5302-5971, Dan Shi https://orcid.org/0000-0001-5658-4314, Martin E.
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