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Jianyin Long on Muck Rack

Jianyin Long

As seen in: Cell Reports, Diabetes Magazine, Texas Medical Center, The Journal of Biological Chemistry
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Articles

PGC1α Is Required for the Renoprotective Effect of lncRNA Tug1 In Vivo and Links Tug1 With Urea Cycle Metabolites

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By Jianyin Long, Koki Mise, Daniel L. Galvan, Paul A Overbeek
| Texas Medical Center
Keywords Animals, Arginase, Diabetic Nephropathies, Disease Progression, Gene Deletion, Kidney, Metabolome, Mice, Inbred C57BL, Mice, Knockout, Mitochondria, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Podocytes, Protective Agents, RNA, Long Noncoding, Urea, Mice Abstract lncRNA taurine-upregulated gene 1 (Tug1) is a promising therapeutic target in the progression of diabetic nephropathy (DN), but the molecular basis of its protection remains poorly understood.
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The Transcription Factor ChREBP Links Mitochondrial Lipidomes to Mitochondrial Morphology and Progression of Diabetic Kidney Disease

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By Jianyin Long, Koki Mise, Philip L. Lorenzi, Naravat Poungavrin
| Texas Medical Center
Keywords Animals, Mice, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Diabetes Mellitus, Diabetic Nephropathies, Gene Expression Regulation, Kidney, Lipidomics, Transcription Factors, lipid metabolism, mitochondria, phospholipid, kidney metabolism, diabetic nephropathy Abstract A substantial body of evidence has established the contributions of both mitochondrial dynamics and lipid metabolism to the pathogenesis of diabetic kidney disease (DKD).
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Role for Carbohydrate Response Element-Binding Protein (ChREBP) in High Glucose-Mediated Repression of Long Noncoding RNA Tug1

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By Jianyin Long, Daniel L. Galvan, Koki Mise, Yashpal S. Kanwar
| Texas Medical Center
Keywords Animals, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Cell Line, Tumor, Gene Expression Regulation, Glucose, Histone Deacetylase 1, Humans, Mice, Podocytes, RNA, Long Noncoding, Repressor Proteins, Transcription, Genetic Abstract Long noncoding RNAs (lncRNAs) have been shown to play key roles in a variety of biological activities of the cell.
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