Jing-hua Yuan on Muck Rack

Jing-hua Yuan

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Articles

Non-telomeric function deficiency of TERT enhances pressure overload-induced mouse cardiac remodeling by activation of CNBP-mediated THBS3/ITGB1 pathway

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By Ying-Ying Liu, Ying-chao Wang, Wen-Yan Gong, Hui Luo, Zhen Chen, Xiao-Ling Xu, JING YANG, Yu-Sheng Cong, Qi-Bin Jiao, Jing-hua Yuan, Xing-wei Zhang
| Nature Verified
Abstract Recent studies show that telomerase reverse transcriptase (TERT) possesses important new biological functions in gene transcription regulation, signal transduction, tumorigenesis, vascular development and mitochondrial DNA protection independent of the maintenance of telomere length. In this study we investigated the role and mechanisms of TERT in regulating the gene expression and signal transduction during pressure overload-induced cardiac remodeling.
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