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Ying-chao Wang on Muck Rack

Ying-chao Wang

As seen in: Nature, Taylor & Francis Online
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Articles

Non-telomeric function deficiency of TERT enhances pressure overload-induced mouse cardiac remodeling by activation of CNBP-mediated THBS3/ITGB1 pathway

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By Ying-Ying Liu, Ying-chao Wang, Wen-Yan Gong, Hui Luo, Zhen Chen, Xiao-Ling Xu, JING YANG, Yu-Sheng Cong, Qi-Bin Jiao, Jing-hua Yuan, Xing-wei Zhang
| Nature Verified
Abstract Recent studies show that telomerase reverse transcriptase (TERT) possesses important new biological functions in gene transcription regulation, signal transduction, tumorigenesis, vascular development and mitochondrial DNA protection independent of the maintenance of telomere length. In this study we investigated the role and mechanisms of TERT in regulating the gene expression and signal transduction during pressure overload-induced cardiac remodeling.
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Three phloridzin derivatives capable of anti-oxidant from Malus toringoides (Rehd) Hughes

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By li Liu, Can Ren, Wei-wei Tian, Ying-chao Wang
| Taylor & Francis Online
Two new phloridzin derivatives 6″-O-(4-hydroxytrans cinnamoyl) phloridzin (1) and 6″-O-(4-hydroxycis-cinnamoyl) phloridzin (3) and one known dihydrochalcones 6″-O-feruloyl phloroside (2) were isolated from the leaves of Malus toringoides (Rehd) Hughes. Their structures were elucidated on the basis of extensive spectroscopic data. The results of zebrafish and FRAP antioxidant kit showed that compound 1–3 had antioxidant effects. No potential conflict of interest was reported by the authors.
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