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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
The lipotoxicity–ferroptosis axis in the transition from insulin resistance to type 2 diabetes: mechanistic integration and therapeutic opportunities
Abstract Insulin resistance is an early feature of type 2 diabetes mellitus (T2DM), but progression to persistent hyperglycemia requires failure of pancreatic β-cell compensation. Lipotoxicity develops when adipose storage and oxidative capacity are exceeded, increasing fatty-acid flux and accumulation of ceramides, diacylglycerols, and oxidizable phospholipids in liver, skeletal muscle, and pancreatic islets.
Efficacy of acupuncture therapies for polycystic ovary syndrome: a network meta-analysis
Abstract Background: Polycystic ovary syndrome (PCOS) is a prevalent gynecological disorder that significantly impairs quality of life and reduces patient confidence in treatment. The efficacy of current Western pharmacological therapies is limited. Acupuncture has shown promise in the management of PCOS, but comparative research on different acupuncture modalities remains scarce.
Novel Alzheimer’s disease-associated variants and genetic interactions identified from UK biobank whole-exome sequencing data using IBI-DT
Abstract Alzheimer’s disease (AD) is a highly heritable neurodegenerative disorder whose genetic architecture remains incompletely understood, particularly with respect to rare variants and higher-order interactions.
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