Asthma and lower airway disease Age-dependent differences in airway inflammation and function in severe uncontrolled asthma Author links open overlay panelJôse Mára de Brito MD, PhD a b, Natália de Souza Xavier Costa MD, PhD a, Diogenes Seraphim Ferreira MD, PhD a, Karina Pierantozzi Vergani MD c, Regina Maria de Carvalho-Pinto MD, PhD d, Luiz Vicente Ribeiro Ferreira da Silva-Filho MD, PhD c, Rodrigo Abensur Athanazio MD, PhD d, Joaquim Carlos Rodrigues MD, PhD c, Thais Mauad MD, PhD a,...