Articles by John Cramer
09.18.26 -- Focusing On Quality Unit Independence With Tatyana Matveeva, Ph.D.
Webinar: Engineering affordability into customizable advanced microscopy platforms Join Ensorcell's Jeff DeFrank for an introduction to Cellular Focus™, a customizable microscopy platform that enables researchers to build application-specific imaging workstations without the high cost and complexity of traditional microscope customization.
Trends in Choking-Related Deaths After Introduction of the Heimlich Maneuver
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available in National Bureau of Economic Research (NBER) Mortality Data at https://www.nber.org/research/data/mortality-data-vital-statistics-nchs-multiple-cause-death-data. These data were derived from the following resources available in the public domain: National Center for Health Statistics (NCHS), https://www.cdc.gov/nchs/.
Benefits Of Preventive Maintenance
By John Cramer, Senior Field Service Engineer Preventive maintenance rarely gets the spotlight, yet it quietly holds bioprocessing systems together. When equipment runs nonstop and bioprocesses shift toward continuous operation, routine service becomes far more than a checkbox—it becomes protection against avoidable disruption. Regular maintenance helps reduce unplanned downtime, preserve product quality, and ensure workflows stay on schedule.
Benefits Of Preventive Maintenance
By John Cramer, Senior Field Service Engineer Preventive maintenance rarely gets the spotlight, yet it quietly holds bioprocessing systems together. When equipment runs nonstop and bioprocesses shift toward continuous operation, routine service becomes far more than a checkbox—it becomes protection against avoidable disruption. Regular maintenance helps reduce unplanned downtime, preserve product quality, and ensure workflows stay on schedule.
The Missouri River
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To the Editor We read with great interest the study by Saadoun et al1 on intraoperative hypothermia and venous thromboembolism (VTE) in microsurgical head and neck reconstruction. The study identified an association between hypothermia and VTE but not flap pedicle thrombosis. Further examination of potential risk factors could clarify the study’s clinical implications.
How Much Lightning Actually Strikes the United States?
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2023: My Year in Horror
As this year marches on at a machine gun pace, I figured I’d check back in with what my horror year looks like now that we have a third of a year already behind us. I’ve written a previous post about the Alter horror website and their stellar YouTube channel consisting of tons of horror short films from around the world. The overall quality of these films is top notch. When I saw that they had a Lovecraft-related collection, naturally I had to watch those asap.
Surgical salvage of human papillomavirus-positive oropharyngeal cancer: Secondary analysis of a randomized controlled trial
Abstract Background Survival outcomes are generally better for human papillomavirus–associated oropharyngeal squamous cell carcinoma (HPV+ OPSCC) than other forms of head and neck cancer. However, less is known about oncologic outcomes, late adverse events, and gastrostomy tube dependence associated with salvage surgery after the failure of definitive chemoradiation in patients with HPV+ OPSCC.
Association of State Opioid Prescription Duration Limits With Changes in Opioid Prescribing for Medicare Beneficiaries
Research Letter Health Care Policy and Law August 9, 2021 JAMA Intern Med. 2021;181(12):1656-1657. doi:10.1001/jamainternmed.2021.4281 Full Text
Incidence of Second Primary Lung Cancer After Low-Dose Computed Tomography vs Chest Radiography Screening in Survivors of Head and Neck Cancer: A Secondary Analysis of a Randomized Clinical Trial | Cancer Screening, Prevention, Control | JAMA Otolaryngolo
Original Investigation From the American Head and Neck Society October 28, 2021 JAMA Otolaryngol Head Neck Surg. Published online October 28, 2021. doi:10.1001/jamaoto.2021.2776 Key Points Question What is the role of lung cancer screening in survivors of head and neck cancer? Findings In this ad hoc secondary analysis of a large randomized clinical trial, 171 head and neck cancer survivors with a long smoking history were identified.
New study sheds light on evolution of photosynthesis
The photosynthetic amoeba Paulinella. Credit: Florian Raunecker A Rutgers-led study sheds new light on the evolution of photosynthesis in plants and algae, which could help to improve crop production. The paper appears in the journal New Phytologist. The scientists reviewed research on the photosynthetic amoeba Paulinella, which is a model to explore a fundamental question about eukaryote evolution: why was there a single origin of algae and plants?
Beneficial bacteria can be restored to C-section babies at birth
Maria Gloria Dominguez-Bello, a professor in Rutgers University-New Brunswick's Department of Biochemistry and Microbiology and Department of Anthropology. Credit: Jeff Heckman Babies born by cesarean section don't have the same healthy bacteria as those born vaginally, but a Rutgers-led study for the first time finds that these natural bacteria can be restored. The study appears in the journal Med.
Rutgers Board of Governors Approves Asset Purchase Agreement for RUCDR Infinite Biologics
The Rutgers Board of Governors today voted to approve an Asset Purchase Agreement, whereby Rutgers will receive $44.4 million to spin out the RUCDR Infinite Biologics lab from Rutgers University-New Brunswick. The newly created company will be called Infinity BiologiX. The new firm has secured significant growth capital to continue the development of RUCDR’s innovative saliva test for COVID-19, as well as to accelerate the expansion of all other RUCDR product and service lines.
Minimizing Excess Opioid Prescribing for Acute Postoperative Pain
The United States is struggling with an epidemic of opioid abuse driven in part by postoperative opioid prescribing patterns. Opioid prescribing after surgery is one of the most common methods of initial opioid exposure and places patients at risk of developing opioid dependency.
Object-related choking deaths down 75% in US children since 1968
Object-related aspiration deaths in U.S. children declined 75% over 50 years, aided in part by policy changes to address choking hazards, according to a study published in JAMA Pediatrics. “Over 20,000 children died preventable deaths in our study period from choking on objects,” John D. Cramer, MD, assistant professor in the department of otolaryngology-head and neck surgery at Wayne State University School of Medicine, told Infectious Diseases in Children.
Object-Related Aspiration Deaths in Children and Adolescents in the United States, 1968 to 2017
During the last 50 years, efforts to prevent aspiration in children have been led by the US Consumer Product Safety Commission, the American Academy of Pediatrics, and the US Public Interest Research Group.1-4 Beginning in 1969 with the Child Protection and Toy Safety Act, regulations on the size of parts in products designed for children, choking hazard warning labels, and public awareness campaigns have been instituted.
The Alternate View - Current Issue | Analog Science Fiction
The Lentz Soliton FTL Drive by John G. Cramer The young Scottish engineer John Scott Russell (1808–1882) was conducting experiments on the most efficient hull design for canal boats when he made a remarkable scientific discovery.
Underwater glacial melting is occurring much faster than predicted
LeConte Glacier. Credit: David Sutherland. Underwater melting of tidewater glaciers is occurring much faster than previously thought, according to a new study by researchers at Rutgers and the University of Oregon. The findings, which could lead to improved forecasting of climate-driven sea level rise, are based on a new method developed by the researchers that for the first time directly measures the submarine melting of tidewater glaciers.
The changing therapeutic landscape of head and neck cancer
Abstract Head and neck cancers are a heterogeneous collection of malignancies of the upper aerodigestive tract, salivary glands and thyroid. In this Review, we primarily focus on the changing therapeutic landscape of head and neck squamous cell carcinomas (HNSCCs) that can arise in the oral cavity, oropharynx, hypopharynx and larynx.
Positron Emission Tomography/Computed Tomography in Evaluation of the Clinically N0 Neck in Head and Neck Squamous Cell Carcinoma
Head and neck squamous cell carcinoma (HNSCC) is characterized by a high propensity for regional lymph node metastases.
Development and Assessment of a Novel Composite Pathologic Risk Stratification for Surgically Resected Human Papillomavirus-Associated Oropharyngeal Cancer | Head and Neck Cancer | JAMA Otolaryngology-Head & Neck Surgery | JAMA Network
[Skip to Content Landing] Figure 1. Adjusted Overall Survival with Traditional Pathologic Risk Stratification vs Composite Risk Stratification Survival curves were adjusted for age, sex, race, comorbidities, insurance status, adjuvant treatment with radiation and/or chemoradiation, and hospital characteristics using a Cox proportional hazard model. A, Human papillomavirus–associated (HPV+) oropharyngeal squamous cell carcinoma (OPSCC) stratified using traditional pathologic risk stratification.
ACW Book Review: Lincoln Under Enemy Fire
Lincoln Under Enemy Fire: The Complete Account of his Experiences During Early’s Attack on Washington In the 1940s, historian James G. Randall asked his graduate students to select one incident from Abraham Lincoln’s life, whether fact, legend or myth, and try to determine exactly what happened. The assignment led John Henry Cramer to investigate what transpired on Lincoln’s famous visit to Fort Stevens during Jubal A. Early’s attack on Washing – ton, D.C., in July 1864.
Risk of Venous Thromboembolism Among Otolaryngology Patients vs General Surgery and Plastic Surgery Patients
Question What is the rate of venous thromboembolism in otolaryngology compared with established-risk surgical fields? Findings This cohort study of 31?896 adult otolaryngology patients found that most patients undergoing otolaryngology operations were at low risk for venous thromboembolism, with rates that are the same or lower than low-risk surgical fields (plastic surgery); however, a subgroup of patients experienced significantly greater rates of venous thromboembolism.
Plasmonic photothermal therapy of atherosclerosis with nanoparticles: long-term outcomes and safety in NANOM-FIM trial
AN Kharlamov (ORCiD 0000-0003-4631-1261) has nothing to financially disclose. JA Feinstein, JA Cramer, JA Boothroyd, EV Shishkina and V Shur have nothing to financially disclose. The authors have no any competing financial interests. Coauthors JA Feinstein, JA Cramer and JA Boothroyd have a special agreement/confidentiality disclosure with Ural Institute of Cardiology (Yekaterinburg, Russia) without financial interest.
What exactly, regression of atherosclerosis or foreign body reaction with hyaline arteriosclerosis, drives transient scaffolding of coronary arteries? A pooled analysis of observational ABSORB studies with a serial multimodality imaging substudy of ABSORB
Publication HistoryPublished online: June 06, 2017Accepted: May 25, 2017; Received in revised form: March 6, 2017; Received: October 13, 2016;
Association of Airway Complications With Free Tissue Transfer to the Upper Aerodigestive Tract With or Without Tracheotomy
Question Is free tissue transfer to the upper aerodigestive tract without tracheotomy associated with an increased rate of airway related complications? Findings In this retrospective cohort study of 861 adult patients, there was no significant difference in the rate of airway-specific complications or death within 30 days of surgery with tracheotomy (8.3%) or without tracheotomy (10.3%).
Princeton-UCLA study finds gray wolves should remain protected
Researchers from Princeton University and the University of California-Los Angeles who investigated the genetic ancestry of North America's wild canines have concluded that the U.S. Fish and Wildlife Service's scientific arguments for removing gray wolves from endangered species protection are incorrect.
Matthew Dentith, The Curious Case of Freeman Dyson and the Paranormal - PhilPapers
Authors Abstract Michael Shermer recently attacked Freeman Dyson for putting forward the claim that there might be something in paranormal claims after all. Whilst I agree with Shermer on many points, I do think you can put forward a plausible theory as to why the Natural Sciences may not describe all phenomena, and that the undescribed phenomena might well be called 'paranormal' because of it.
Settling the Controversy Over Photo of Lee Harvey Oswald
Body A new study by Dartmouth researchers helps to refute one of the most famous conspiracy theories in U.S. history. Dartmouth researchers built and posed a physiologically plausible 3-D model of Lee Harvey Oswald to match his appearance in the famous photo. By adding the appropriate mass to each part of the 3-D model, they were able to perform a balance analysis that revealed that although Oswald appears off-balance, his pose is stable.
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