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John Packer

  • Professor and Director, HRREC at University of Ottawa
As seen in: The Globe and Mail, The Toronto Star, The Hill, BioRxiv, Montreal Gazette, Ottawa Citizen, O Canada, NewsBreak, National Observer, LNP and
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Articles

AI, Business and the Road Ahead: One Practitioner's Perspective

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By John Packer
| LNP Verified
Heceta Head lighthouse at sunset, from an elevated point of view. Florence, Lane county, Oregon, USA. I entered the accounting profession in 1980 when our tools were a calculator, pencils, and green ledger sheets. Since then, I've lived through three significant technological changes that made me faster and more capable: the personal computer, electronic spreadsheets, and the internet. Now I'm using artificial intelligence.
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Difficult budget decision: Understanding the proposed tax rate

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By John Packer
| marblefallsmessenger.com
Each year, the Marble Falls City Council is entrusted with one of our most important responsibilities: adopting a budget that provides the services our community depends on while being responsible with the dollars our residents entrust to us. This year, that responsibility has required some particularly difficult conversations. At Tuesday's city council meeting, we held a roll call vote to advance a proposed property tax rate of $0.58 per $100 of taxable valuation to a public hearing on Sept. 15.
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Atypical Protein Kinase C Promotes its own Asymmetric Localisation by Phosphorylating Cdc42 in Polarising Cells

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By John Packer, Alicia Gascon Gubieda, Aaron Brooks, Lars N Deutz
| BioRxiv
Abstract Atypical protein kinase C (aPKC) is a major regulator of cell polarity. Acting in conjunction with Par6, Par3 and the small GTPase Cdc42, aPKC becomes asymmetrically localised and drives the polarisation of cells. aPKC activity is crucial for its own asymmetric localisation, suggesting a hitherto unknown feedback mechanism contributing to polarisation. Here we show in the C. elegans zygote that the feedback relies on aPKC phosphorylation of Cdc42 at serine 71.
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