John Tregoning on Muck Rack

John Tregoning

London
As seen in: Bangalore Mirror, Color Research & Application, Nature, The Guardian, Science Magazine, Cell Press, The Lancet, Scroll.in, Times Higher Education, The Quietus and
Professor of Vaccine Immunology Author of science books 'A Wise and Witty Scientist' Tweets my opinion Rep'd @LittleHardman Publisher @OneworldNews
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Articles

Procrastination, productivity and inspiration: how research is like designing video games

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By John Tregoning
| Nature
Bennett Foddy says research can be creative, like game design.Credit: Gabriel Cuzzillo I am a vaccine-immunology researcher and, since childhood, an enthusiastic (but mostly talentless) amateur gamer. I have an enduring love for the text-based adventure games I played in the 1980s, as well as for classics from the 1990s and early 2000s, such as Doom, Half Life and Grand Theft Auto III.
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Noncanonical amino acids enable plug and play vaccine platform in the ALiCE cell free system

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By Arjen Schots, Livia Spiga, John Tregoning, Jonathan Brown, Jie Zhou, Hannes Juergens, Ricarda Finnern, Charles Williams, Jorge Armero-Gimenez, Janis Schleusner, Ruud H. P. Wilbers
| Nature
Abstract Non-canonical amino acids (ncaas) are increasingly used in vaccinology to improve vaccine adaptability and immunogenicity. Cell-free protein synthesis (CFPS) offers a promising route for site-specific ncaa incorporation, but conventional prokaryotic CFPS systems show limitations to produce complex proteins requiring post-translational modifications while eukaryotic systems have historically been difficult to scale and show low protein yields.
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Science funding needs fixing - but not through chaotic reforms

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By John Tregoning
| Nature
The UK science ecosystem is in limbo. On 1 February, the country’s national science-funding agency, UK Research and Innovation (UKRI), announced large changes to how research grants will be judged and awarded. Although the precise details are still emerging, the UKRI open letter states an aim to “focus and do fewer things better” (see go.nature.com/4rnhghn). Support for curiosity-driven research will be preserved, we are told.
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