Jouke Jan Wedman on Muck Rack

Jouke Jan Wedman

As seen in: Cell Press, The Journal of Biological Chemistry
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Articles

Opt1 imports CoA precursors as glutathione mixed disulphides

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By Jouke Jan Wedman, Michael Chang, Bart van Lingen, Ralph Hardenberg
| The Journal of Biological Chemistry Verified
Keywords coenzyme A metabolism pantetheine screen yeast Introduction The metabolic cofactor coenzyme A (CoA) is essential to all organisms, ranging from prokaryotes to plants and animals. CoA is required for the citric acid cycle, fatty acid biosynthesis, and fatty acid degradation (1–3). Post-translational modifications including acylation, CoAlation and 4′-phosphopantetheinylation also depend on CoA (4).
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Coenzyme A precursors flow from mother to zygote and from microbiome to host

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By Yi Yu, Jouke Jan Wedman, Hjalmar Permentier, Niels Plomp
| Cell Press Verified
Aghajanian S. Worrall D.M. Identification and characterization of the gene encoding the human phosphopantetheine adenylyltransferase and dephospho-CoA kinase bifunctional enzyme (CoA synthase). Biochem. J. 2002; 365: 13-18 Evolution of maternal and zygotic mRNA complements in the early Drosophila embryo. PLoS Genet. 2018; 14: e1007838 Balibar C.J. Hollis-Symynkywicz M.F. Tao J.
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