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Articles by Jun Tu
Growth factor VEGF-B sustains intestinal Tfh cell stemness to restrict Taurinivorans outgrowth and microbiota-driven obesity
Keywords VEGF-B VEGFR-1 T follicular helper cells Tfh cells stemness senescence IgA Taurinivorans obesity Introduction Mucosal immunosurveillance plays an essential role in metabolic regulation, particularly via immunoglobulin A (IgA)-mediated control of the gut microbiota.1,2,3,4,5 This surveillance is executed in large part by IgA, which continuously monitors the intestinal microbiota to maintain gut homeostasis and prevent microbial encroachment that could disrupt host metabolism.1,2,3,4,5...
SUMOylation activates ECHS1 for adaptive catabolism in lung cancer
Abstract Cellular metabolism dynamically adapts to nutrient fluctuations, yet the regulatory mechanisms underlying this plasticity remain incompletely understood. In particular, the adaptive activation mechanism of enoyl-CoA hydratase short-chain 1 (ECHS1), a key mitochondrial enzyme for fatty acid and amino acid catabolism, is poorly characterized.
Fatigue life assessment and analysis based on weak perturbation effects
ABSTRACT Fatigue damage in materials is a critical factor affecting the safe operation of nuclear power components. Magnetic response is highly sensitive to material degradation processes and serves as an important means for assessing material integrity. Based on theoretical analysis, this paper establishes a coupling model between low-frequency weak-perturbation inductance signals and fatigue damage.
Research on coordination of the e-commerce platform supply chain considering tripartite ai investments
Ayuda Buscar en la ayuda Buscar en la ayuda Research on coordination of the e-commerce platform supply chain considering tripartite ai investments Zijiao Sun [1] ; Jun Tu [2] [1] Liaoning Technical University, China [2] Wuxi University, China Localización: Journal of Theoretical and Applied Electronic Commerce Research, ISSN-e 0718-1876, Vol. 20, Nº.
Frontiers | Cognitive function and uric acid levels among low-income rural Chinese aged ≥60 years without hyperuricemia
ORIGINAL RESEARCH article Volume 12 - 2025 | https://doi.org/10.3389/fmed.2025.1753357 This article is part of the Research TopicLinking Chronic Disease Burden, Multimorbidity, and Frailty in Geriatric MedicineView all articles 1 Introduction The Global Burden of Disease (GBD) study estimates that over 56.9 million people worldwide are affected by Alzheimer’s disease and other dementias, resulting in 36.3 million disability-adjusted life years (DALYs) lost (1).
Associations between TyG-Related Indices and Bone Health: A Cross-Sect
Back to Journals » Diabetes, Metabolic Syndrome and Obesity » Volume 18 Original Research Metabolic Disorders and Complications Authors Jia F, Lu Y , Wen H, Tu J, Ning X, Wang J , Li P Received 6 November 2024 Accepted for publication 22 April 2025 Published 7 May 2025 Volume 2025:18 Pages 1445—1458 DOI https://doi.org/10.2147/DMSO.S505024 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Professor Jae Woong Sull Fang...
Establishment and Application of a Triplex Real-Time Reverse-Transcription Polymerase Chain Reaction Assay for Differentiation of PEDV, TGEV and PKV
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Investigation of an Active Focusing Planar Piezoelectric Ultrasonic Transducer
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Evolutionary Game Analysis of Governments’ and Enterprises’ Carbon-Emission Reduction
1. Introduction In the context of global climate change and environmental degradation, the reduction of carbon emissions by governments and enterprises has become a focus of global attention. According to the BP Statistical Review of World Energy (2023), the carbon dioxide emissions generated in 2022 increased by 0.8% compared to 2021 [].
Evolutionary Game Analysis on Safety Supervision for Coal Mine Considering Speculative Behavior
Safety work plays a pivotal role in the production process of coal mines, and the safety of coal mining production is related to the national economy and people’s livelihood. Due to the huge demand for coal and the harsh environment of coal mining, the safety production and supervision of coal mines is a prominent problem and challenge [1].
Internal and External Pipe Defect Characterization via High-Frequency Lamb Waves Generated by Unidirectional EMAT
4. Experiments 4.1. Experimental Platform The experimental system platform is shown in Figure 6, consisting of an oscilloscope, Ritec-5000 high-energy pulse transmitter/receiver, test iron pipe, and the developed electromagnetic ultrasonic sensors. In the experiment, an iron pipe with a diameter of 270 mm and a wall thickness of 6 mm was used as the detection object, as shown in Figure 6.
Topic tones of analyst reports and stock returns: A deep learning approach
Processing of Japanese language The Japanese writing system is formed by three different sets of characters: Hiragana, Katakana, and Kanji. It is also common to see Arabic numerals and Latin script in Japanese text (Bond et al., 2016). In Japanese, there is a variety of classes of words, some of which are common with English: noun, verb, adjective and adverb. Verbs and adjectives are inflected, whereas nouns and adverbs are not.
Monoclonal antibody‐based systematic identification of SUMO1‐modification sites reveals TFII‐I SUMOylation is involved in tumor growth
RESEARCH ARTICLE Yalan Chen, Kexin Liu, and Geqiang Zhang contributed equally to this study. Abstract SUMOylation plays an essential role in diverse physiological and pathological processes. Identification of wild-type SUMO1-modification sites by mass spectrometry is still challenging. In this study, we produced a monoclonal SUMO1C-K antibody recognizing SUMOylated peptides and proposed an efficient streamline for identification of SUMOylation sites.
Competition between Green and Non-Green Travel Companies: The Role of Governmental Subsidies in Green Travel
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Jun Tu 1, Juan Du 1,* and Min Huang 2 1 College of Science, Liaoning Technical University, Fuxin 123000, China 2 College of Information Science and Engineering, Northeastern University, Shenyang 110819, China * Author to whom correspondence should be addressed.
Debonding Detection in Aluminum/Rigid Polyurethane Foam Composite Plates Using A0 Mode LAMB Wave EMATs
Abstract : Aluminum/rigid polyurethane foam composite plates (ARCPs) are widely used for thermal insulation. The interface debonding generated during manufacturing degrades the thermal insulation performance of an ARCP. In this study, the debonding of an ARCP, a composite plate with a porous and damped layer of rigid polyurethane foam (RPUF), was detected using A0 mode Lamb wave electromagnetic acoustic transducers (EMATs).
Energy Transfer Efficiency Based Nonlinear Ultrasonic Testing Technique for Debonding Defects of Aluminum Alloy Foam Sandwich Panels
3.2. Sample Preparation In order to validate the effectiveness of the proposed method in thin plate detection, four kinds of aluminum plates with thicknesses of 1 mm, 2 mm, 3 mm and 10 mm were selected to make test samples. An amount of 3 M polyurethane foam tape is used as the core layer material.
Incentive Contracts for a Queueing System with a Strategic Server: A Principal-Agent Perspective
7. Numerical Results This section uses numerical experiments to investigate the performance of the server’s service effort, the sojourn time of consumers, and the profit of the queueing system under different decision-making scenarios. This study discusses the impact of different decision-making scenarios on the optimal results of the queueing system. This study also discusses contract options for the owner, server, and queueing system. The basic parameter settings are shown in Table 5.
Safety Improvement of Sustainable Coal Transportation in Mines: A Contract Design Perspective
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Jun Tu 1, Liangdong Wan 1,* and Zijiao Sun 2 1 College of Science, Liaoning Technical University, Fuxin 123000, China 2 School of Business Administration, Liaoning Technical University, Huludao 125105, China * Author to whom correspondence should be addressed.
Quantitative Identification Method for Glass Panel Defects Using Microwave Detection Based on the CSAPSO-BP Neural Network
Open AccessArticle by Jun Fang 1,2, Zhiyang Deng 1,2,*, Jun Tu 1,2 and Xiaochun Song 1,2 1 School of Mechanical Engineering, Hubei University of Technology, Wuhan 430068, China 2 Hubei Key Laboratory of Modern Manufacturing Quality Engineering, Wuhan 430068, China * Author to whom correspondence should be addressed.
The Footprints Of Urbanization, Industrialization, And Agriculture On River Beds: Heavy Metal Contamination Assessment And Source Identification In River Sediments In Eastern China | Science Trends
Image by stanbialik via Pixabay is licensed under CC0 River beds are usually untouched by human feet, unless the rivers are dry. However, the heavy metals in river beds carry the footprints of various human activities, such as urbanization, industrialization, and agriculture. After heavy metals generated from these activities are discharged into rivers, they are adsorbed by suspended matters, and then suspended matters carrying heavy metals will eventually sink into river sediments.
SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism
Highlights • Sirt3 SUMOylation suppresses its catalytic activity in mitochondria • Fasting induces SENP1 translocation into mitochondria to de-SUMOylate Sirt3 • The SENP1-Sirt3 axis promotes fatty acid oxidation and energy production • Sirt3 SUMOylation mutation antagonizes HFD-induced obesity via energy expenditure Summary Sirt3, as a major mitochondrial nicotinamide adenine dinucleotide (NAD)-dependent deacetylase, is required for mitochondrial metabolic adaption to various stresses.
Enhanced 808 nm driven Ce3+ doped red-emitting upcoversion nanocrystals by intercalated nanostructure
We report the red but weak upconversion luminescence of core-shell-shell structured upconversion nanocrystals (NaYF4:Yb/Ho/Ce@NaYF4:Nd@NaYF4) under excitation at 808 nm due to high surface Ce3+ concentration in core nanocrystals hinder the energy transfer from shell Nd3+ to core Yb3+.
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