Junbo Chen
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Articles by Junbo Chen
Unilateral π-Expanded Self-Assembled Hole Transport Multilayers for Binary Organic Solar Cells With Efficiency of 20.77%
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adfm77327-sup-0001-SuppMat.docx11.2 MB Supporting File: adfm77327-sup-0001-SuppMat.docx.
Malignant mesothelioma of the tunica vaginalis testis initially misdiagnosed as a benign testicular hydrocele: a case report
Abstract Objective: To improve the clinical understanding, diagnostic accuracy, and therapeutic management of mesothelioma of the tunica vaginalis testis. Methods: We present a case of mesothelioma of the tunica vaginalis in a patient recently admitted to our institution. The clinical characteristics, histopathological features, and therapeutic modalities used are described. FAPI PET/CT was applied as an adjunctive diagnostic tool for preoperative surgical planning.
Activation of Nerve Growth Factor signaling limits the response to lenvatinib in hepatocellular carcinoma
Abstract Resistance to lenvatinib remains a major barrier in the treatment of advanced hepatocellular carcinoma (HCC), underscoring the urgent need to elucidate the underlying mechanisms and identify actionable therapeutic targets. In this study, we identified a neurosecretory factor derived from HCC cells, Nerve Growth Factor (NGF), as a critical mediator of lenvatinib resistance.
2′-Fucosyllactose Alleviates Metabolic Hypertension in Mice via Gut Microbiota Modulation and Involvement of the LPS/TLR4 Signaling Click to copy article link Article link copied!
Cite Jump to ExpandCollapse Bioactive Constituents, Metabolites, and FunctionsApril 2, 2026 2′-Fucosyllactose Alleviates Metabolic Hypertension in Mice via Gut Microbiota Modulation and Involvement of the LPS/TLR4 Signaling Click to copy article linkArticle link copied! Junbo Chen Junbo Chen Key Laboratory of Food Bioengineering (China National Light Industry), College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China Food Laboratory of...
Thiophene Expanded Self‐Assembled Monolayer as Hole Transport Layer for Organic Solar Cells with Efficiency of 20.78%
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma70076-sup-0001-SuppMat.docx18.4 MB Supporting Information References 1, , , , , , , , , Adv. Energy Mater. 2018, 8, 1801892. 2, , , , , , , , , , , , , , , , , , , , , , Energy Environ. Sci. 2019, 12, 3356. 3, , , , , , , Science 2024, 383, 1236. 4, , , , , , , , , , , , , , , , , , , , , , , , , Nature 2024, 632, 301. 5, , , , , , , , , , , , , , Nature 2023, 620, 545.
CLDN4 palmitoylation promotes hepatic-to-biliary lineage transition and lenvatinib resistance in hepatocellular carcinoma
Keywords: Claudin4 hepatic-to-biliary transition lenvatinib resistance palmitoylation hepatocellular carcinoma Introduction Lineage transition is an intricate and poorly understood process in which the original lineage of a cancer undergoes alteration, leading to the emergence of a new cancer lineage. Due to the dynamic nature of cancer, tumor cell subpopulations evolve continuously throughout malignant progression and systemic treatment.
Traditional Value Identity and Mental Health Correlation Among Chinese Adolescents
1. Introduction In the 21st century, the rapid pace of technological advancements has led to changes in daily life that are far more substantial than those experienced by our ancestors. For countries with a rich history and traditional culture, such as China, traditional values play an essential role in shaping the moral framework of both individuals and society.
Subject-Agnostic Transformer-Based Neural Speech Decoding from Surface and Depth Electrode Signals
Abstract Objective: This study investigates speech decoding from neural signals captured by intracranial electrodes. Most prior works can only work with electrodes on a 2D grid (i.e., Electrocorticographic or ECoG array) and data from a single patient. We aim to design a deep-learning model architecture that can accommodate both surface (ECoG) and depth (stereotactic EEG or sEEG) electrodes.
An Autonomous Intelligent Liability Determination Method for Minor Accidents Based on Collision Detection and Large Language Models
1. Introduction As global urbanization accelerates, car ownership has surged and urban traffic density has increased significantly [1,2,3], posing significant challenges to traffic management. This situation not only increases the frequency of minor traffic accidents, but also exacerbates traffic congestion.
Construction of a streptavidin-based dual-localized DNAzyme walker for disease biomarker detection
Construction of a streptavidin-based dual-localized DNAzyme walker for disease biomarker detection† A dual-localized DNAzyme walker (dlDW) was constructed by utilizing multiple split DNAzymes with probes, and their substrates are separately localized on streptavidin and AuNPs, serving as walking pedals and tracks, respectively. Based on dlDW, biosensing platform was successfully constructed and showed great potential application in clinical disease diagnosis.
OG: Equip vision occupancy with instance segmentation and visual grounding
Occupancy prediction tasks focus on the inference of both geometry and semantic labels for each voxel, which is an important perception mission. However, it is still a semantic segmentation task without distinguishing various instances.
Antibody signatures in hospitalized hand, foot and mouth disease patients with acute enterovirus A71 infection
EV-A71 specific human monoclonal antibodies We next sought to produce mAbs based on the BCR variable gene sequences of the plasmablasts. We firstly examined the BCR clonotype enrichment in the 228 plasmablasts. B cells that have the same variable gene usage and identical amino acids in the third complementarity determining region (CDR3) of both heavy and light chains were grouped into the same clonotypes. There are 201 unique clonotypes, including 78 IgG, 55 IgA, and 68 IgM.
Ultracompact Integrated Mode-Order Converter and Reciprocal Optical Diode with Etched Subwavelength Structures
Open AccessArticle by Danfeng Zhu 1,*, Dingnan Deng 1, Junbo Chen 1, Shaobin Qiu 1, Jing Li 2 and Han Ye 2 1 School of Physics and Electrical Engineering, Meizhou Intelligent Photoelectric Detection Application Engineering Technology Research Center, Jiaying University, Meizhou 514015, China 2 State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, Beijing 100876, China * Author to whom correspondence should be addressed.
Guanidine-based biomimetic hydrides for carbon dioxide reduction
Guanidine-based biomimetic hydrides for carbon dioxide reduction† Junbo Chen, ab Haibo Yu, ab Davin Tan *cd and Richmond Lee *ab Abstract The feasibility of various bespoke guanidine-based compounds as biomimetic hydrides were assessed by Density Functional Theory (DFT).
A Simple Strategy Based on Combinatorial Gold Nanoparticle Sizes for Enhanced Sensitivity in Colorimetric Bioanalysis
A Simple Strategy Based on Combinatorial Gold Nanoparticle Sizes for Enhanced Sensitivity in Colorimetric Bioanalysis Huan Du, Yanwen Jin, Xiaoke Zheng, nansheng cheng, Junbo Chen and Xiandeng Hou Abstract Taking advantage of salt-induced aggregation, gold nanoparticles (AuNPs) have been intensively employed in non-cross-linked strategy (NCLs) for colorimetric bioanalysis.
Performance Simulation of Permeable Concrete Materials Combined with Nanotechnology in Rainwater Management
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Recent Advances in Surface Modifications of Elemental Two-Dimensional Materials: Structures, Properties, and Applications
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Monitoring nucleic acid amplification process by UiO-66-NH2-based fluorescence sensor
Monitoring nucleic acid amplification process by UiO-66-NH2-based fluorescence sensor Changjia Hu, Junbo Chen, Peng Yang, Lijie Du, Linyin Xia, Juan He and Xiandeng Hou Abstract Herein, we developed a nucleic acid amplification process monitoring scheme by use of UiO-66-NH2, in which pyrophosphate ion (PPi) released from the amplification can competitively coordinate with Zr to weaken the ligand-to-metal charge transfer and cause fluorescence recovery, thus reflecting the amplification process.
Activating the Neutral pH Photozymatic Activity of g-C3N4 Nanosheet through Post-Synthetic Incorporation of Pt
Activating the Neutral pH Photozymatic Activity of g-C3N4 Nanosheet through Post-Synthetic Incorporation of Pt Xue Li, Xianming Li, Qian Chen, Junbo Chen and Peng Wu Abstract The catalytic activity of photozyme can be regulated through light irradiation time and intensity, but it still suffers from low activity in physiological neutral pH (typically, pH < 5). Herein, through simple post-synthetic incorporation of Pt, the neutral pH activity of g-C3N4 nanosheet (CNNS) was activated.
A novel angiotensin-converting enzyme inhibitory peptide from rabbit meat protein hydrolysate: Identification, molecular mechanism, and antihypertensive effect in vivo
A novel angiotensin-converting enzyme inhibitory peptide from rabbit meat protein hydrolysate: Identification, molecular mechanism, and antihypertensive effect in vivo Junbo Chen, Xiaodong Yu, Wangxiang Huang, Chen Wang and Qiyi He Abstract Bioactive peptides exhibiting angiotensin-converting enzyme (ACE) inhibitory effects and extracted from natural foods have potential as healthy and safe therapeutics for high blood pressure.
Stub Column Behavior of Cold-Formed High-Strength Steel Circular Hollow Sections under Compression
Downloaded 0 times Technical Papers Abstract This paper describes an experimental and numerical investigation on the stub column behavior of cold-formed high-strength steel (HSS) circular hollow sections (CHSs). A total of 16 stub column specimens fabricated from Q460, Q690, and Q960 steel plates were tested. Axial load-end shortening responses and failure modes of the stub column tests are presented and discussed.
Mesoscale structure of wrinkle patterns and defect-proliferated liquid crystalline phases
Greenhouse gas emissions in the first decades of the 21st century are likely to affect global sea level for centuries, and limiting long-term sea-level rise might require stringent near-term emission reductions.
Toehold-regulated Competitive Assembly to Accelerate Kinetics of Graphene Oxide-based Biosensors
Toehold-regulated Competitive Assembly to Accelerate Kinetics of Graphene Oxide-based Biosensors With effective adsorption and quench efficiency, graphene oxide (GO) can be utilized for biomolecules sensing, such as nucleic acid or protein detection. In theses assays, fluorephore-labeled nucleic acid (reporter) is usually absored by GO first, and followed by adding the target molecules to bind the reporter, thus restoring the fluorescence signal.
Symplectic Analysis of Wrinkles in Elastic Layers With Graded Stiffnesses
Wrinkles in layered neo-Hookean structures were recently formulated as a Hamiltonian system by taking the thickness direction as a pseudo-time variable. This enabled an efficient and accurate numerical method to solve the eigenvalue problem for onset wrinkles. Here, we show that wrinkles in graded elastic layers can also be described as a time-varying Hamiltonian system. The connection between wrinkles and the Hamiltonian system is established through an energy method.
Selective reduction-based highly sensitive and homogeneous detection of iodide and melamine using chemical vapour generation-atomic fluorescence spectrometry
P. Chen, P. Yang, R. Zhou, X. Yang, J. Chen and X. Hou, Chem. Commun., 2018, Accepted Manuscript , DOI: 10.1039/C8CC01186A If you are not the author of this article and you wish to reproduce material from it in a third party non-RSC publication you must formally request permission using RightsLink. Go to our Instructions for using RightsLink page for details.
Hepatitis B Virus e Antigen Activates the Suppressor of Cytokine Signaling 2 to Repress Interferon Action
We initially evaluated the role of HBeAg in the phosphorylation of STAT1 induced by IFN in cells transfected with pCMV-HBeAg or pCMV-Tag2B and treated with recombinant human IFN-? (rhIFN-?) or recombinant human IFN-? (rhIFN-?). HBeAg was highly expressed in pCMV-HBeAg transfected cells and mainly secreted to the cell culture supernatant (Fig. S1A). Phosphorylation of STAT1 (p-STAT1) was enhanced by rhIFN-? or rhIFN-?1 but repressed by HBeAg (Fig. 1A), and p-STAT1 in nucleus was enhanced by rhIFN-?
Amplified binding-induced homogeneous assay through catalytic cycling of analyte for ultrasensitive protein detection
By using the principle of binding-induced DNA assembly, we have developed a novel homogeneous assay that is able to convert an affinity protein binding event into a predesigned DNA assembly. The assembled DNA sequence can be ligated into an intact DNA strand and hundreds of DNA hairpins can be cleaved by a nicking endonuclease. Each cleavage releases a single-stranded DNA (ssDNA) probe that is initially caged in the DNA hairpin.
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