Karina Carvalho

Highlights • Phosphatidylcholine/phosphatidylethanolamine (PC/PE) induce TGF-β signaling in monocytes • Bile acids (BAs) induce type I IFN in monocytes • Efficacy of dengue vaccine Butantan-TV003 requires a broad nAb response to all four serotypes • nAb response to Butantan-TV003 is associated with pre-vaccination levels of BAs and PC/PE Summary Protective immunity to dengue virus (DENV) requires antibody response to all four serotypes.

1. Introduction Long COVID Syndrome, know as Long COVID, can be described as the persistence signs and symptoms that continue or develop for more than 4 weeks after acute COVID-19 infection (1). During clinical evaluation, differential diagnosis and the identification of associated pathologies unrelated to SARS-CoV-2 infection are essential (2). Manifestations of Long COVID occur in approximately 50%–80% of previously symptomatic patients with COVID-19 who have recovered (3).

Freitas, Joana Lúcia Alexandre [1] ; Mancini, Karina Carvallho [2] [1] Faculdade de Ensino Superior de Linhares-Faceli [2] Universidade Federal do Espírito Santo Localización: Kiri-Kerê - Pesquisa em Ensino, ISSN-e 2526-2688, Nº. 7, 2019, págs.