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ArticleOnline now102832Open access Affiliations & Notes 1Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95064, USA 2Department of Electrical and Computer Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA 3Department of Molecular, Cellular and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA 4Department of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, CA 95064, USA...
Keywords biocomputing organoid intelligence artificial intelligence reinforcement learning electrophysiology electrical stimulation in vitro cortical organoid closed-loop control causal connectivity Research topic(s) CP: stem cell research CP: neuroscience Introduction The brain has an unmatched capability for intelligent and dynamic information processing—deep artificial neural networks require over five layers to achieve an adequate approximation of a single biological neuron1—yet...
Abstract The analysis of tissue cultures, particularly brain organoids, requires a sophisticated integration and coordination of multiple technologies for monitoring and measuring. We have developed an automated research platform enabling independent devices to achieve collaborative objectives for feedback-driven cell culture studies.
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