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Kathleen C. Barnes on Muck Rack

Kathleen C. Barnes

As seen in: Nature, Genome Medicine, The Journal of Allergy & Clinical Immunology, Alive, Annals of Allergy, Asthma & Immunology, Taste For Life, Natural Awakenings Magazine
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Articles

Determinants of mosaic chromosomal alteration fitness - Nature Communications

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By Yash Pershad, Adrienne M. Stilp, Braxton D. Mitchell, Joshua Lewis, Nathalie Chami, Zhe Wang, Kathleen C. Barnes, Nathan Pankratz, Myriam Fornage, Bruce M. Psaty, Joshua C. Bis, Jeong Yun, Andrew Johnson, Rasika A. Mathias, Laura M. Raffield, April P. Carson, Stephen S. Rich, Jerome I. Rotter, Xiuqing Guo, Dan M. Roden, Nora Franceschini, Alex P. Reiner, Paul L. Auer, Paul Scheet, Siddhartha Jaiswal, Joshua Weinstock, Hannah Poisner
| Nature Verified
Abstract Clonal hematopoiesis (CH) is characterized by the acquisition of a somatic mutation in a hematopoietic stem cell that results in a clonal expansion. These driver mutations can be single nucleotide variants in cancer driver genes or larger structural rearrangements called mosaic chromosomal alterations (mCAs). The factors that influence the variations in mCA fitness and ultimately result in different clonal expansion rates are not well understood.
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Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing - Nature Genetics

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By Yasminka A. Jakubek, Adrienne M. Stilp, Justin Wong, Zuhal Özcan, Kathleen C. Barnes, Joshua C. Bis, April P. Carson, Matthew P. Conomos, Myriam Fornage, Xiuqing Guo, Joshua Lewis, Mitchell J Machiela, Taralynn M. Mack, Rasika A. Mathias, Braxton D. Mitchell, Nathan Pankratz, Patricia A. Peyser, Michael Preuss, Bruce M. Psaty, Laura M. Raffield, Ramachandran S. Vasan, Stephen S. Rich, Jerome I. Rotter, Jennifer Smith, Jeong Yun, Yun Li Verified, Alexander Bick, Paul Scheet
| Nature Verified
Abstract Megabase-scale mosaic chromosomal alterations (mCAs) in blood are prognostic markers for a host of human diseases. Here, to gain a better understanding of mCA rates in genetically diverse populations, we analyzed whole-genome sequencing data from 67,390 individuals from the National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine program.
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Natural Solutions for Arthritis

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By Kathleen C. Barnes
| Taste For Life Verified
Problems with some Cox 2-inhibiting drugs have created concern among the millions of Americans who suffer from osteoarthritis (OA). The good news is that natural alternatives are available. Safe and effective, some of these pain relievers have been shown to slow the progression of osteoarthritis and even reverse damage. Inflammation and Pain All types of arthritis are characterized by chronic inflammation.
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