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Articles by Keith Latham
Embryonic Mediators of Embryo–Uterus Communication, Implantation and Pregnancy
1 Introduction Successful reproduction in eutherian mammals requires the establishment of intimate connections between the embryonic cells and the uterus.
Paternal Effects in Mammalian Reproduction: Functional, Environmental, and Clinical Relevance of Sperm Components in Early Embryos and Beyond
1 Introduction Parental effects on embryo development and progeny phenotype are widespread across diverse phylogenetic groups. Maternal effects, wherein oocyte components exert extensive effects on such processes as gene regulation, embryo physiology, axial patterning, and cell fate specification, are mechanistically well-characterized (Ruebel and Latham 2020), although in mammals, certain mechanisms of maternal effects play lesser roles than in other animal taxa.
Early Cell Lineage Formation in Mammals: Complexity, Species Diversity, and Susceptibility to Disruptions Impacting Embryo Viability
1 Introduction The formation of the earliest mammalian cell lineages at the blastocyst stage has long intrigued mammalian developmental biologists because this divergence is visually apparent morphologically and ultrastructurally (Calarco and Brown 1969; Nadijcka and Hillman 1974).
Preimplantation genetic testing: A remarkable history of pioneering, technical challenges, innovations, and ethical considerations
1 INTRODUCTION Preimplantation genetic testing (PGT) has emerged as a powerful companion to assisted reproduction technologies (ARTs) in addressing needs in human reproductive and genetic medicine. Over 400 genetic disorders are available for analysis by PGT (Kuliev & Rechitsky, 2017), with an expanding capacity to detect aneuploidies and chromosomal structural rearrangements.
Promising assisted reproductive technologies come with ethical, legal and social challenges - a developmental biologist and a bioethicist discuss IVF, abortion and the mice with two dads
A few days after successful fertilization, an embryo becomes a rapidly dividing ball of cells called a blastocyst. Juan Gaertner/Science Photo Library via Getty Images Assisted reproductive technologies are medical procedures that help people experiencing difficulty having or an inability to have biological children of their own.
Promising assisted reproductive technologies come with ethical, legal and social challenges - a developmental biologist and a bioethicist discuss IVF, abortion and the mice with two dads
Assisted reproductive technologies are medical procedures that help people experiencing difficulty having or an inability to have biological children of their own. From in vitro fertilization to genetic screening to creation of viable eggs from the skin cells of two male mice, each new development speaks to the potential of reproductive technologies to expand access to the experience of pregnancy.
Promising assisted reproductive technologies come with ethical, legal and social challenges - a developmental biologist and a bioethicist discuss IVF, abortion and the mice with two dads
(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Keith Latham, Michigan State University and Mary Faith Marshall, University of Virginia (THE CONVERSATION) Assisted reproductive technologies are medical procedures that help people experiencing difficulty having or an inability to have biological children of their own.
Promising assisted reproductive technologies come with ethical, legal and social challenges - a developmental biologist and a bioethicist discuss IVF, abortion and the mice with two dads
(THE CONVERSATION) Assisted reproductive technologies are medical procedures that help people experiencing difficulty having or an inability to have biological children of their own. From in vitro fertilization to genetic screening to creation of viable eggs from the skin cells of two male mice, each new development speaks to the potential of reproductive technologies to expand access to the experience of pregnancy.
Predictive modeling of oocyte maternal mRNA features of five mammalian species reveals potential shared and species-restricted regulators during maturation | Physiological Genomics
Oocyte maturation is accompanied by changes in abundances of thousands of mRNAs, many degraded and many preferentially stabilized.
Promising assisted reproductive technologies come with ethical, legal and social challenges - a developmental biologist and a bioethicist discuss IVF, abortion and the mice with two dads Original
Assisted reproductive technologies are medical procedures that help people experiencing difficulty having or an inability to have biological children of their own. From in vitro fertilization to genetic screening to creation of viable eggs from the skin cells of two male mice, each new development speaks to the potential of reproductive technologies to expand access to the experience of pregnancy.
Promising assisted reproductive technologies come with ethical, legal and social challenges - a developmental biologist and a bioethicist discuss IVF, abortion and the mice with two dads | Wire | perutribune.com
(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Keith Latham, Michigan State University and Mary Faith Marshall, University of Virginia kAmW%wt r~}'t#$p%x~}X pDD:DE65 C6AC@5F4E:G6 E649?@=@8:6D 2C6 >65:42= AC@465FC6D E92E 96=A A6@A=6 6IA6C:6?4:?8 5:77:4F=EJ 92G:?8 @C 2? :?23:=:EJ E@ 92G6 3:@=@8:42= 49:=5C6? @7 E96:C @H?] uC@> :? G:EC@ 76CE:=:K2E:@? E@ 86?6E:4 D4C66?:?8 E@ 4C62E:@?
Promising assisted reproductive technologies come with ethical, legal and social challenges - a developmental biologist and a bioethicist discuss IVF, abortion and the mice with two dads | Wire | h-ponline.com
(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Keith Latham, Michigan State University and Mary Faith Marshall, University of Virginia kAmW%wt r~}'t#$p%x~}X pDD:DE65 C6AC@5F4E:G6 E649?@=@8:6D 2C6 >65:42= AC@465FC6D E92E 96=A A6@A=6 6IA6C:6?4:?8 5:77:4F=EJ 92G:?8 @C 2? :?23:=:EJ E@ 92G6 3:@=@8:42= 49:=5C6? @7 E96:C @H?] uC@> :? G:EC@ 76CE:=:K2E:@? E@ 86?6E:4 D4C66?:?8 E@ 4C62E:@?
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