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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Analysis of 173,303 exomes and genomes in the Pakistan Genome Resource
Abstract Naturally occurring loss-of-function variants in human genes enable drug target discovery because they mimic pharmacological inhibition of proteins. However, the study of these genetic variants is constrained by their rarity. Sequencing of diverse populations, particularly those enriched in familial relatedness, has been postulated to promote discovery of rare genetic variants1,2,3.
Tofacitinib plus methotrexate versus tofacitinib monotherapy in rheumatoid arthritis: A comprehensive evidence synthesis and critical analysis.
Abstract Objective: To compare the benefits of Tofacitinib with Methotrexate vs Tofacitinib alone with respect to efficacy and safety over a period of 6 months. Study Design: Randomized Controlled Trial. Setting: Outpatient Department of Rheumatology, Madinah Teaching Hospital, Faisalabad. Period: 01st August,2025 to 31st Jan,2026. Methods: Consisted of 60 people enrolled as per the inclusion criteria (ACR/EULAR 2010 Criteria), after getting approval from the ethics review committee.
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