Krishna Prasad Subedi on Muck Rack

Krishna Prasad Subedi

As seen in: PNAS, Cell Press
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Articles

STIM2 targets Orai1/STIM1 to the AKAP79 signaling complex and confers coupling of Ca2+ entry with NFAT1 activation

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By Ga-Yeon Son, Krishna Prasad Subedi, Hwei Ling Ong, Lucile Noyer
| PNAS Verified
Given the considerable uncertainty arising from underlying disease and social dynamics, detailed refinements to models often create a misleading sense of precision.
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STIM2 Induces Activated Conformation of STIM1 to Control Orai1 Function in ER-PM Junctions

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By Hwei Ling Ong, Xibao Liu, Krishna Prasad Subedi, Ga-Yeon Son
| Cell Press Verified
Extended Conformation of STIM2 Promotes Recruitment of STIM1 and STIM1/Orai1 Coupling   STIM2 Triggers STIM1 Activation to Enhance Orai1 Function in Cells with High ER-[Ca2+] The expanded C-terminal OASF region of STIM2 shows the different mutations that were made to probe the domains and conformational status that determine STIM2 function (Figure 1Figure 1A and Tables S1x Download (1.56 MB ) Document S1.
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