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Articles by Kun Yu
Modular Robotic NOSES-II for Mid-Rectal Cancer: A Preliminary Feasibility Study of a Structured Surgical Procedure
The authors have declared no competing interest. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
Research on an automatic multi-color drawing module with multi-gripper pen-holder for industrial robots
Abstract Drawing is an important artistic expression form, with extensive research on automated robotic drawing. To address the demand for millimeter-level precision automatic color-changing drawing in industrial robots, this study proposes a novel robotic multi-color drawing system based on the KUKA KR10R1420 platform, with a multi-gripper pen-holding module (2/3/4/5 grippers) as the core component.
Geochemistry and Hydrocarbon Generation of Coal Measures in the Daji Region, the Southeastern Margin of the Ordos Basin
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. References , and . 2013. “Variation of Gas Flow Properties in Coal With Probe Gas, Composition and Fabric: Examples From Western Canadian Sedimentary Basin.” International Journal of Coal Geology 108: 47–52. , , , , and . 2023.
Targeting m6A-SCG2-TAMs axis overcomes 5-FU resistance in colorectal cancer via a multi-omics model
Abstract Chemoresistance to 5-fluorouracil (5-FU) remains a critical barrier in colorectal cancer (CRC) management. This study integrates multi-omics data from 26,192 human samples to elucidate the RNA methylation-mediated crosstalk between tumor-associated macrophages (TAMs) and tumor cells.
A CEL simulation approach for penetration-leveling of the multi-bucket foundation incorporating the temperature analogy method
Abstract The multi-bucket foundation is widely used in offshore engineering, and the foundation inclination during installation necessitates leveling to ensure its bearing capacity. Although the numerical simulation offers an efficient and rapid approach of validating leveling strategies, the significant large deformation during foundation leveling makes conventional approaches unable to directly simulate, let alone reliably capture the associated seepage distribution characteristics.
Responsive Phase Gradient Metasurface for Laser Stealth and Dynamic Thermal Camouflage
Z.Yuan, Y.Liu, K.Yu, et al. “Responsive Phase Gradient Metasurface for Laser Stealth and Dynamic Thermal Camouflage.” Laser & Photonics Reviews (2026): e71278. https://doi.org/10.1002/lpor.71278 Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.
Safeguarding Springer Nature collections: the integrity checks you should know about
Join us for a look behind the scenes of Springer Nature collections in a special blog series. In today’s blog, Kun Yu, Director of Collections Management and Acquisition, explains how Springer Nature collections safeguard integrity, and why this is so important for the researchers who publish in them.
Protective effect of baicalein from Pinellia ternate on Alzheimer’s disease cell injury: a network pharmacology, molecular docking, and molecular dynamics study
Abstract Introduction: Alzheimer’s disease (AD) constitutes the primary leading cause of dementia. Pinellia ternata (Thunb.) Breit. is a traditional Chinese herb with unclarified potential therapeutic effects against AD. This study aimed to explore the therapeutic potential and underlying mechanism of Pinellia ternata (Thunb.) Breit. in the treatment of AD. Methods: The bioactive components and corresponding targets of Pinellia ternata (Thunb.) Breit.
Pathological complete response following immunotherapy in dMMR/MSI-H ascending colon primary squamous cell carcinoma: a case report
Abstract Primary colon squamous cell carcinoma (SCC) is an extremely rare malignancy and associated with a poor prognosis. This case report describes a patient with deficient mismatch repair/microsatellite instability-high (dMMR/MSI-H) ascending colon SCC, who was treated at our institution.
Gap-Filling and Crystallization Kinetics Regulation in VTD/Spray Hybrid Perovskite Solar Cells
Cite Jump to ExpandCollapse ArticleMarch 3, 2026 Gap-Filling and Crystallization Kinetics Regulation in VTD/Spray Hybrid Perovskite Solar Cells Click to copy article linkArticle link copied! Kun Yu Kun Yu State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China Tian Zhong Tian Zhong State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070,...
Hypoxia‐preconditioned adipose‐derived stem cells with injectable small intestinal submucosa for enhanced cartilage repair in osteoarthritis
This study introduces a novel method for osteoarthritis (OA) treatment by improving the therapeutic potential of adipose-derived mesenchymal stem cells (ADSCs). By using hypoxia preconditioning and embedding ADSCs in an injectable small intestinal submucosa (SIS) scaffold, the composite material greatly enhanced cartilage repair in OA.
Supramolecular Interlocking Produces Mechanically Anisotropic, Robust, and Tough Biomimetic Ionogels
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adma72209-sup-0001-SuppMat.pdf1.7 MB Supporting File: adma72209-sup-0001-SuppMat.pdf. References 1, , , et al., “Glassy Gels Toughened by Solvent,” Nature 631 (2024): 313–318, https://doi.org/10.1038/s41586-024-07564-0.
Carbon Structure Evolution of Middle- and High-Rank Coal during Coalification: Implication for Methane Production and Adsorption
1. Introduction Click to copy section linkSection link copied! Coal is a solid combustible organic rock formed by higher plants buried underground through complex biochemical and physicochemical changes. (1−3) Compared with low-porosity rock, the coal structure is more sensitive to temperature, pressure, and other environmental conditions, and its nanoscale pore structure is an important occurrence space of unconventional energy.
Can ChatGPT as a generative AI tool enhance university student academic achievement?
ABSTRACT The Chat Generative Pre-trained Transformer (ChatGPT) is one of the most representative generative AI (GenAI) that has been used widely in higher education. However, ChatGPT’s usage has raised some concerns about its effectiveness in improving academic performance. This study uses a meta-analysis to examine the impact of ChatGPT on university student academic achievement.
Targeting SIRT3 to Ameliorate Diabetic Cardiomyopathy: Progress in Mechanistic Research and Prospects for Clinical Translation
First comprehensive integration of SIRT3's multi-dimensional protective roles in DCM, spanning energy metabolism, mitochondrial quality control, cardiomyocyte death suppression, and endothelial repair. A new perspective on breaking through the treatment dilemma of “high blood sugar memory”. It is proposed that SIRT3 agonists may bypass the limitations of traditional hypoglycemic therapy, providing a new strategy to overcome the “metabolic memory” of diabetic myocardium.
Frontiers | Comprehensive analysis of metabolism-related genes in sepsis reveals metabolic-immune heterogeneity and highlights GYG1 as a potential therapeutic target
Introduction Sepsis is a life-threatening syndrome characterized by dysregulated host responses to infection, leading to life-threatening organ dysfunction and high mortality worldwide (1–3). Despite advances in supportive care, effective targeted therapies remain elusive, largely due to the substantial biological heterogeneity of the disease.
Inhibition of BRD4 activates the AKT-SIRT3 signaling pathway to suppress apoptosis and attenuate hyperoxia-induced lung injury
Introduction Oxygen supplementation is widely applied to alleviate severe respiratory failure in critical pneumonia and acute lung injury (ALI) patients (Sohn et al., 2010). However, sustained high-concentration oxygen exposure paradoxically induces systemic oxidative damage, with the pulmonary system being particularly susceptible to oxygen toxicity (Hong et al., 2021; Huang et al., 2024).
Common-path polarization holography with partial coherent illumination for single-shot Jones matrix measurement
Polarization holographic microscopy (PHM) enables precise characterization of the Jones matrix of anisotropic media (AM), presenting ubiquitous applications in material characterization and biomedical diagnostics. However, existing PHM systems struggle to achieve single-shot imaging while maintaining high spatiotemporal phase sensitivity, limiting the measurement accuracy and imaging efficiency.
Versatile infrared characterization platform: emissivity for opaque materials and emissivity-transmissivity-driven reflectivity for semi-transparent materials
Existing systems are limited to opaque or semi-transparent materials, impeding comparative analysis under identical conditions. To address this limitation, we present a versatile infrared characterization platform for measuring the emissivity of opaque materials and simultaneously determining the emissivity, transmissivity, and reflectivity of semi-transparent ones.
Strategy and mechanism for external-induced recovery of lithium-ion battery internal short circuit
Keywords lithium-ion battery internal short circuit fault detection Introduction Lithium-ion batteries have been deployed in many electrification fields such as battery electric vehicles (BEVs),1 battery energy storage systems (BESSs),2 and micro-grids,3 owing to their high energy density, long cycle lifespan, and low cost. With a large number of BEVs and large-scale BESSs poured into use, battery safety is crucial to reduce accidents.
Forest or trees? Evidence for global processing via an information board study into cues utilised in phishing identification
ABSTRACT We examined the patterns of cues people utilised as they attempted to classify emails as legitimate or phishing via a novel approach – an information board study. In this paradigm, participants had to click on email elements to examine them, revealing which cues are utilised in the decision-making process as well as viewing duration. An online email classification task (87 Ps) was presented, including a between-subjects’ manipulation of cognitive load.
Revealing the Hazard of Mild Electrical Abuse on the Safety Characteristics of NaNi1/3Fe1/3Mn1/3O2 Cathode Sodium‐Ion Battery
1 Introduction With the rapid development of renewable energy and electric transportation, battery technology has become a cornerstone in the field of energy storage.[1] Sodium-ion batteries (SIBs) have garnered increasing attention as a potential alternative to lithium-ion batteries (LIBs) due to their abundant resources, low cost, and relatively high safety.[2, 3] While sodium-ion batteries exhibit slightly lower energy density compared to lithium-ion batteries, they show promising...
Femtosecond laser fabrication metasurface emitter for multispectral camouflage
The powerful electromagnetic capability of a metasurface makes it a good candidate for thermal emission manipulation toward promising infrared (IR) camouflage and thermal management technology. Here, a metasurface-based infrared is fabricated to achieve multispectral camouflage as well as radiative cooling simultaneously.
Flexible multilayer film structure for visible-laser-infrared compatible camouflage
With the rapid advancement of detection technologies, the demand for multi-band compatible camouflage solutions has significantly increased. In this study, we propose a flexible meta-coating based on a polyimide (PI) substrate, featuring a double Fabry–Perot cavity for effective camouflage across visible–near-infrared laser-infrared bands.
Recent Advances in Materials, Synthesis, and Reaction Model of Particle Adsorbent for Flue Gas Desulfurization
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Engineering Asymmetric Electronic Structure of Co─N─C Single‐Atomic Sites Toward Excellent Electrochemical H2O2 Production and Biomass Upgrading
Conflict of Interests The authors declare no conflict of interest. Supporting Information Filename Description anie202502383-sup-0001-SuppMat.pdf13.9 MB Supporting Information References 1, , , , Chem. Soc. Rev. 2024, 53, 8137–8181. 2, , , , , , , , Nat. Rev. Chem. 2019, 3, 442–458. 3, , , , , Adv. Mater. 2024, 36, 2400140. 4, , , , Chem. Eng. J. 2023, 456, 141042. 5, , , , , , , , , , Nat. Commun. 2020, 11, 5478. 6, , , , , , , , , Adv. Mater. 2021, 33, 2103266. 7, , , , Ind. Eng. Chem. Res. 1994, 33, 277–284.
Underwater Acoustic Signal LOFAR Spectrogram Denoising Based on Enhanced Simulation
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Facet Engineering Modulates d‐π* Hybridization for Boosting Antimicrobial Activity
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202418440-sup-0001-SuppMat.docx18.3 MB Supporting Information References 1a) , , , , , , , , , , , Science 2019, 364, 41; b) , , , , , , , , , , , , , , Nat. Sustainability. 2019, 2, 445; c) , , , , Nat. Microbiol. 2019, 4, 1432. 2a) , , , , , , , , , ACS Nano 2014, 8, 10682; b) , , , Nat. Rev. Microbiol. 2013, 11, 371; c) , , , , Chem. Soc. Rev. 2015, 44, 7787; d) , , , , , Nat. Commun.
Dynamic Impedance Model of Low-Voltage Electric Shock in Animals Considering the Influence of Water Electrolysis
1. Introduction Electric shocks in low-voltage systems are serious accidents. Victims cannot easily break free and can be in life-threatening danger quickly. In China, the annual death toll from electric shock accidents reaches as high as 8000 [1]. Approximately 70% of these electric shock incidents occur in low-voltage distribution networks [2]. With the increasing demand for electricity, there are growing expectations for the safety of distribution networks [3,4,5].
Health‐Related Quality of Life Among Discharged Patients With Hemophagocytic Lymphohistiocytosis: A Follow‐Up Study
CI confidence interval CNS central nervous system HLH hemophagocytic lymphohistiocytosis HPS hemophagocytic syndrome HRQoL health-related quality of life HSCT hematopoietic stem cell transplantation MAS macrophage activation syndrome PedsQL pediatric quality of life inventory pHLH primary HLH PICU pediatric intensive care unit SE standard error VIF variance inflation factor 1 Background Hemophagocytic lymphohistiocytosis (HLH), also known as hemophagocytic syndrome (HPS), is a potentially...
A MSTNDel73C mutation with FGF5 knockout sheep by CRISPR/Cas9 promotes skeletal muscle myofiber hyperplasia
eLife assessment The authors present a useful analysis of the phenotype of sheep in which the muscle developmental regulator myostatin has been mutated in a FGF5 knockout background. The goal was to produce sheep with a "double-muscled" phenotype, yet the genetically engineered sheep exhibited meat with a smaller cross-sectional area and higher number of muscle fibers. The work extends the extensive body of knowledge already published in this area.
Robust phylogenomics settles controversies of classification and reveals evolution of male embolic complex of the Laufeia clade (Araneae, Salticidae, Euophryini)
Conflict of interest None declared. Supporting Information Filename Description cla12597-sup-0001-Fig.S1.pdfPDF document, 231.5 KB Fig. S1. Phylogenetic inferences from maximum-likelihood (ML) method and Bayesian inference (BI); node value: ultrafast bootstrap (ML)/posterior probability (BI). cla12597-sup-0002-Fig.S2.pdfPDF document, 218.3 KB Fig. S2. Phylogenetic inference from maximum parsimony (MP) method, inferred by TNT. cla12597-sup-0003-Fig.S3.pdfPDF document, 222.5 KB Fig. S3.
Accurately Measuring the Infrared Spectral Emissivity of Inconel 601, Inconel 625, and Inconel 718 Alloys during the Oxidation Process
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Facet Engineering Boosts Interfacial Compatibility of Inorganic‐Polymer Composites
1 Introduction Polymer composites dispersed with inorganic particles (IPCs) possess markedly enhanced mechanical properties compared to pure polymers, which has attracted considerable interest in the field of aerospace, automotive, electrical and electronic, construction, et al.[1] It is generally believed that the mechanical properties of the IPCs, especially for plasticity, represent the most critical performance metric, with interfacial compatibility between inorganic and polymer materials...
Enhancing Benzylamine Electro‐Oxidation and Hydrogen Evolution Through in‐situ Electrochemical Activation of CoC2O4 Nanoarrays
Conflict of Interests The authors declare no conflict of interest. Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Research on the Configuration of a 100% Green Electricity Supplied Zero-Carbon Integrated Energy Station
1. Introduction The extensive use of fossil fuels over the past century has led to the emission of greenhouse gases, exacerbating global climate warming and causing significant real and potential impacts on human living conditions. Reducing greenhouse gas emissions is urgent and is a powerful driver for the global transition to low-carbon energy.
Adaptive Bi-Directional LSTM Short-Term Load Forecasting with Improved Attention Mechanisms
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Effects of Fresh Groundwater and Seawater Mixing Proportions and Salt-Freshwater Displacement on Coastal Aquifer Microbial Communities
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Multispectral radiation thermometry platform based on wireless data transmission
In metal smelting, precise temperature control is of vital importance for reaction rates, efficiency, and product quality. Traditional methods such as thermocouples have inherent limitations, but multispectral radiation thermometry (MRT) offers high resolution and reliability. This paper proposes a multispectral radiation thermometry platform featuring wireless data transmission, which enables remote data transfer and precise temperature measurements.
Research Progress and Recent Advances in Development and Applications of Infrared Stealth Materials: A Comprehensive Review
Conflict of Interest The authors declare no conflict of interest. References 1, , , Phys. Rev. Appl. 2020, 13, 024063. 2, , , , , , , Adv. Mater. Technol. 2017, 2, 1700005. 3, , , , , Infrared Phys. Technol. 2022, 123, 104142. 4, , , , Ceram. Int. 2023, 49, 5559. 5, , , , J. Korea Inst. Military Sci. Technol. 2019, 22, 81. 6, , Aerospace Sci. Technol. 2021, 110, 106490. 7, Acta Phys. Pol. A 2009, 116, 389. 8, , Aeronaut. J. 2002, 106, 629. 9, , , J. Thermal Sci. Eng. Appl. 2022, 14, 011004. 10, , , Infrared Technol. 2016, 38, 96.
Reaction-Thin Film Evaporation Coupling Technology for Highly Efficient Synthesis of Higher Alkyl Methacrylate
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Nanoclay Mediated Self‐Promoted Reactive Oxygen Species Releasing Enables Efficient Antimicrobial
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202407875-sup-0001-SuppMat.docx24 MB Supporting Information References 1a) , , , , , , , , , , , , Adv. Mater. 2018, 31, 1804838; b) , , , Science 1999, 284, 1318; c) , , , , , , , , , Adv. Mater. 2023, 35, 2302431. 2a) , , , Chem. Rev. 2019, 119, 4881; b) , , Chem. Rev. 2017, 117, 11302. 3a) , , , , , , , , , , , Adv. Funct. Mater. 2024, 34, 2306319; b) , , , , , , , , , , , , , , , , , Adv.
Quality characteristics and cooking‐induced changes on phenolic compounds of dried green tea noodles
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. REFERENCES American Association of Cereal Chemists (AACC). (2000). Approved Methods of the AACC ( 10th ed.). AACC. , , , , , , , & (2015). Effect of green tea powder on thermal, rheological & functional properties of wheat flour and physical, nutraceutical & sensory analysis of cookies. Journal of Food Science and Technology, 52(9), 5799–5807. https://doi.org/10.1007/s13197-014-1701-3 , , & (2013).
Active Fault-Locating Scheme for Hybrid Distribution Line Based on Mutation of Aerial-Mode Injected Pulse
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Preliminary study on pharmacokinetics and antitumor pharmacodynamics o
Xin Cheng,1– 4,* Rui Pan,1,3– 5,* Junze Tang,1,4 Kun Yu,1,4 Hailiang Zhang,1,3– 5 Xiaoyu Zhao1,4 1College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming, 650500, People’s Republic of China; 2The Key Laboratory of External Drug Delivery System and Preparation Technology in University of Yunnan Province, Kunming, 650500, People’s Republic of China; 3Yunnan Key Laboratory of Dai and Yi Medicines, Kunming, 650500, People’s Republic of China; 4Laboratory...
Artificial Metalloenzyme‐Catalyzed Enantioselective Carboamination of Alkenes
Introduction The synthetic chemistry repertoire offers multiple tools for the selective (mono)functionalization of alkenes, alkynes, and allenes.1, 2 In recent years, the difunctionalization alkenes has attracted significant attention, as it provides a step-economical approach for the vicinal difunctionalization alkenes.3 Among these reactions, carboamination occupies a prominent place as it offers an efficient strategy to forge a C−N and a C−C bond simulatenously.1, 4-9 Research on...
Artificial Metalloenzyme‐Catalyzed Enantioselective Carboamination of Alkenes
Introduction The synthetic chemistry repertoire offers multiple tools for the selective (mono)functionalization of alkenes, alkynes, and allenes.1, 2 In recent years, the difunctionalization alkenes has attracted significant attention, as it provides a step-economical approach for the vicinal difunctionalization alkenes.3 Among these reactions, carboamination occupies a prominent place as it offers an efficient strategy to forge a C−N and a C−C bond simulatenously.1, 4-9 Research on...
Integrated approach for simultaneously measuring thermophysical parameters of semi-transparent materials
To concurrently determine the thermophysical parameters of semi-transparent materials, a novel, to the best of our knowledge, integrated approach for concurrent measurement is proposed. In the measurement setup, a high-temperature radiation source and a beam reducer are employed to minimize the influence of background radiation.
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