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Articles by Lada Kohoutová
Brain responses to heartbeat are altered in patients with iRBD
Isolated REM sleep behavior disorder (iRBD), a condition characterized by strong physical reactions to vivid, often violent dreams, is one of the earliest warning signs of brain changes seen in Parkinson's disease or dementia with Lewy bodies, sometimes appearing years before diagnosis.
Brain responses to heartbeat are altered in patients with iRBD
Patients with isolated REM sleep behaviour disorder show altered brain responses to heartbeat during wakefulness, offering a potential biomarker of the disorder. Isolated REM sleep behaviour disorder (iRBD), a condition characterised by strong physical reactions to vivid, often violent, dreams, is one of the earliest warning signs of brain changes seen in Parkinson’s disease or dementia with Lewy bodies, sometimes appearing years before diagnosis.
Patient-specific functional networks track early cognitive alterations and minor hallucinations in Parkinson’s disease
Abstract Minor hallucinations (MHs) affect up to 40% of patients with Parkinson’s disease (PD) and are early indicators of cognitive decline. Unlike previous group-level studies, connectome-based brain fingerprinting enables the capture of individualized neural features.
Toward a unified framework for interpreting machine-learning models in neuroimaging
Abstract Machine learning is a powerful tool for creating computational models relating brain function to behavior, and its use is becoming widespread in neuroscience. However, these models are complex and often hard to interpret, making it difficult to evaluate their neuroscientific validity and contribution to understanding the brain.
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