Lada Kohoutová

Isolated REM sleep behavior disorder (iRBD), a condition characterized by strong physical reactions to vivid, often violent dreams, is one of the earliest warning signs of brain changes seen in Parkinson's disease or dementia with Lewy bodies, sometimes appearing years before diagnosis.

Patients with isolated REM sleep behaviour disorder show altered brain responses to heartbeat during wakefulness, offering a potential biomarker of the disorder. Isolated REM sleep behaviour disorder (iRBD), a condition characterised by strong physical reactions to vivid, often violent, dreams, is one of the earliest warning signs of brain changes seen in Parkinson’s disease or dementia with Lewy bodies, sometimes appearing years before diagnosis.

Abstract Minor hallucinations (MHs) affect up to 40% of patients with Parkinson’s disease (PD) and are early indicators of cognitive decline. Unlike previous group-level studies, connectome-based brain fingerprinting enables the capture of individualized neural features.