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Laura Blackie

As seen in: Nature, Yahoo Canada, The Conversation, Science Magazine, BioRxiv, Cell Press, Atlantico

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Articles

The sex and reproductive plasticity of intestinal muscles instruct gut size

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By Alessandro Mineo, Laura Blackie, Alexandra Milona, Emily Strachan, Pedro Gaspar, Nuno Miguel Luis, Alvaro Castano-Medina, Tomotsune Ameku, Bryon Silva, Anadika R. Prasad, Clara L. Essmann, Jake Jacobson, Todd Fallesen, Vanessa Dao, Sanjay Khadayate, George Young, Filipe Cabreiro, Frank Schnorrer, Irene Miguel-Aliaga
| Cell Press Verified
Results To investigate potential sex differences in intestinal muscle, we re-analyzed publicly available single-nucleus Drosophila transcriptomes profiling all adult tissues from male and (mated) female flies.26 Focusing on midgut visceral muscle clusters from both midgut-specific and cross-tissue datasets, we compared the sexes.
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Why do some people feel life is so unfair? Understanding this may help explain conspiracy beliefs Original

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By Daniel Jolley, Laura Blackie
| The Conversation Verified
Most people set out in life wanting to believe the world is fair. They expect people to wait their turn in queues, to be treated equally in their job, and to be rewarded for hard work. These expectations influence how they understand the world around them, and shape their responses to it. But what happens when life repeatedly challenges those assumptions? Psychologists have long been interested in this question.
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Myc sustains sex-biased organ zonation in the Drosophila intestine

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By Christopher Amourda, Laura Blackie, Pedro Gaspar, Laura Martin-Coll, Anadika R. Prasad, Andrew House, Minna Holopainen, Hanna Ruhanen, Nicole Lamichane, Dafni Hadjieconomou, Tomotsune Ameku, Alessandro Mineo, Milly Coxhead, Irene Soler-Saez, Cristina Galiana-Roselló, Francisco J. Garcia-Garcia, Francisco José García-García, Yi-Fang Wang, Cyrille Alexandre, Ville Hietakangas, Reijo Käkelä, Santiago Vernia, Irene Miguel-Aliaga
| Cell Press Verified
Keywords gut sexual dimorphism enterocyte lipid Myc organ zonation doublesex drosophila ploidy endoreplication Introduction Males and females frequently differ in both physiology and disease susceptibility.1,2,3,4,5 Sex differences arise from the interplay between sex hormones and the cell-intrinsic effects of sex chromosomes—sometimes termed “cellular sex.” At first glance, the hormonal contribution to physiology may appear more pronounced than that of cellular sex.
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