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Lawrence Liu

As seen in: Nature, Wiley Online Library, MDPI, Product Hunt, BioRxiv, DEV Community, PeerJ, ONCOLOGY journal, Automotive Fleet, Embedded Computing Design and
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Articles

Association between diabetic control and progression of monoclonal gammopathy of undetermined significance to multiple myeloma

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By Lawrence Liu, Byron S. Sigel, Mei Wang, Nikhil Grandhi, Martin W. Schoen, Kristen M Sanfilippo, Kenneth Carson, Murali Janakiram, Tzeyu L. Michaud, Graham A. Colditz, Theodore Thomas, Su-Hsin Chang
| Nature Verified
Abstract Diabetes Mellitus (DM) is a risk factor for multiple myeloma (MM), but the relationship between diabetic control and risk of progression to MM in patients with monoclonal gammopathy of undetermined significant (MGUS) is unclear. We conducted a retrospective cohort study of US Veterans diagnosed with MGUS from 10/1/1999-12/31/2023 with prior DM. MGUS and MM diagnoses were confirmed using published natural language processing-assisted models.
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Quantifying the contribution of modifiable risk factors for progression of MGUS to multiple myeloma in a Veteran population

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By Byron S. Sigel, Mei Wang, Lawrence Liu
| Wiley Online Library Verified
aHR multivariable-adjusted hazard ratio AO Agent Orange aPAF multivariable-adjusted population attributable fraction BMI body mass index CCI Charlson Comorbidity Index CI confidence interval CIF cumulative incidence function Ig immunoglobulin IQR interquartile range M- monoclonal MGUS monoclonal gammopathy of undetermined significance MM multiple myeloma NLP natural language processing TCDD 2,3,7,8-tetrachlorodibenzo-p-dioxin VHA Veterans Health Administration 1 INTRODUCTION Multiple myeloma...
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Interactive Brokers Market Data Subscription: Which One Do I Actually Need in 2026?

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By Lawrence Liu
| DEV Community
When I first opened my Interactive Brokers account, I stared at the market data subscription page for a solid 20 minutes. There were dozens of options — bundles, individual exchanges, Level 1, Level 2, professional vs. non-professional classifications. IB's own pricing page is a wall of tables with zero practical guidance. I was terrified of subscribing to the wrong thing and getting charged for data I didn't need.
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