linlin zhao

Abstract Digital transformation is profoundly reshaping rural socio-economic landscapes and livelihood trajectories worldwide. However, the spatially differentiated mechanisms through which specific mobile social platforms reconfigure farmers’ social-spatial networks and the consequent heterogeneous livelihood outcomes remain insufficiently theorized and empirically underexplored within an integrated analytical framework.

Abstract Aberrant signaling through tumor necrosis factor receptor 1 (TNFR1) drives chronic inflammation and necroptotic cell death, yet selective therapeutic strategies remain limited. Here, humanized nanobodies targeting TNFR1 were developed and characterized. Biolayer interferometry and cell-based analyses showed that these nanobodies remained in the nanomolar affinity range to TNFR1 after humanization and showed no detectable binding to TNFR2 under the tested conditions.

Abstract Obtaining exact solutions to nonlinear partial differential equations (NLPDEs) remains a fundamental challenge in mathematical physics, with traditional methods often limited by problem-specific constraints and tedious manual derivations.