Lisa Encarnacion

Keywords ALS neurodegeneration spinal cord motor neuron selective vulnerability snRNA-seq snATAC-seq spatial transcriptomics cell states microglial activation Introduction Amyotrophic lateral sclerosis (ALS) is a progressive disorder distinguished by degeneration of motor neurons in the brain and spinal cord. Motor neuron loss impairs mobility, dexterity, speech, and swallowing and ultimately causes fatal paralysis. ALS is a cruelly rapid disease.

Q: What is your organization's name? Q: When and why did the organization start? How has it grown? A: Three nonprofit hospice care providers, Horizon Hospice & Palliative Care, JourneyCare and Midwest Palliative & Hospice CareCenter, each with more than 30 years of experience serving their communities, combined in 2015 to form one agency, JourneyCare.