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Articles by Liwei Chen
Gestational diabetes mellitus and risk of long-term cardiometabolic disease
Abstract Gestational diabetes mellitus (GDM), or hyperglycaemia first diagnosed during pregnancy, is associated with adverse outcomes for the mother and offspring. In this narrative review, we first summarize the epidemiological evidence regarding long-term maternal and offspring cardiometabolic consequences of GDM, including the role of heterogeneity in the aetiology of GDM in shaping the long-term effects of GDM exposure.
Repairability and Active Defect Utilization in Direct Regeneration of Lithium-Ion Battery Cathodes
1 Introduction Lithium-ion batteries (LIBs) have reshaped the global energy landscape over the past two decades [1]. The first wave of power batteries has now entered large scale retirement period [2]. According to the International Energy Agency, the global volume of retired LIBs will exceed 100 GWh by 2025 and climb above 300 GWh by 2030 (Figure 1a,b) [3, 4]. Improper disposal of these retired batteries not only wastes strategic metal resources but also poses severe environmental risks [5].
TWF1 inhibition overcomes cisplatin resistance in NSCLC by inducing ferroptosis via p53-dependent SLC7A11 repression and autophagy-mediated glutathione metabolism reprogramming
Abstract Non-small-cell lung cancer (NSCLC) ranks among the most prevalent causes of cancer-related mortality worldwide, with cisplatin-based chemotherapy being a cornerstone of clinical treatment despite the inevitable emergence of drug resistance. This study systematically investigated the molecular mechanisms underlying cisplatin resistance in NSCLC, focusing on the role of TWF1 in regulating ferroptosis. Mechanistic analyses revealed that TWF1 acts as a dual-function suppressor of ferroptosis.
Lower Risk of Developing Gestational Diabetes Mellitus in the Group Prenatal Care Model
1 Introduction Gestational diabetes mellitus (GDM), defined as glucose intolerance with onset or first recognition during pregnancy, is one of the most common pregnancy complications, affecting ~7% of pregnancies in the United States [1]. Individuals with GDM are at greater risk for other pregnancy complications such as maternal hypertensive disorders, preterm and caesarean delivery [2], as well as elevated risks of developing type 2 diabetes and cardiovascular diseases in their later life [3-5].
cPLA2α inhibition potentiates anti-PD-1 immunotherapy in lung adenocarcinoma via remodeling tumor microenvironment
Abstract Although immune checkpoint inhibitors (ICIs) against PD-1/PD-L1 have revolutionized lung adenocarcinoma (LUAD) therapy, resistance and low response rates persist. Cytoplasmic phospholipase A2α (cPLA2α), a key enzyme in inflammatory pathways, promotes tumor progression, yet its immunomodulatory role in LUAD is unclear. Here, cPLA2α overexpression is found in LUAD tissues, correlating with poor prognosis.
Cell-autonomous co-stimulatory function of membrane-bound CD100 promotes activation and differentiation of HBcAg-specific CD8 + T cells
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Abstract Background: CD100/SEMA4D functions as a critical co-stimulatory molecule in T cell responses, existing in both membrane-bound (mCD100) and soluble (sCD100) forms. Previous studies have shown that CD100 enhances CD8+ T cell responses indirectly by promoting the maturation and activation of antigen-presenting cells, thereby facilitating viral clearance.
By Mengxiao Zhao, Liwei Chen, Yuhang Chen, Lu Wang Verified, Xuecheng Yang, Kathrin Sutter, Mengji Lu, Jieliang Chen, Xin Zheng, Dongliang Yang, Liang Wang, Jia Liu
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Frontiers in Immunology
College Students’ Social Media Use and Digital Well-Being: The Chain Mediating Roles of Social Capital and Digital Trust
Back to Journals » Psychology Research and Behavior Management » Volume 19 Authors Zhang H, Chen L , Deng W Received 27 May 2026 Accepted for publication 11 August 2026 Published 3 September 2026 Volume 2026:19 628039 DOI https://doi.org/10.2147/PRBM.S628039 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Prof.
3D-printed multiscale-ordered hierarchical frameworks for rapid atmospheric water harvesting
Abstract Freshwater scarcity poses an escalating threat to global sustainability, yet sorption-based atmospheric water harvesting offers a compelling solution by extracting moisture directly from air, independent of geographic constraints. A critical bottleneck limiting sorption-based atmospheric water-harvesting capacity, however, remains the sluggish kinetics of sorption–desorption cycling.
Entropy-Mediated Solvation Enables Interfacial Equilibrium for Stable Ah-Level Zinc Metal Batteries
S.Li, Y.Liu, L.Chen, et al. Angewandte Chemie International Edition. (2026): e8484996. https://doi.org/10.1002/anie.8484996 Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description anie72497-sup-0001-SuppMat.docx19.9 MB Supporting File 1: anie72497-sup-0001-SuppMat.docx.
Experimental Study on Vertical and Lateral Bearing Characteristics of Rock-Socketed Long Piles at Deeply Backfilled Sites in Nuclear Power Engineering
You are already at the latest version The foundation of nuclear power plants is special as large-scale earth filling is often required. The properties of the backfill soil differ significantly from naturally deposited soils with regard to deformation and bearing capacity. For pile foundations, a thick backfill layer near the top may change the bearing mode around the pile.
Racial and ethnic disparities in type 2 diabetes: does visceral fat play a role? Evidence from the MESA study
Abstract In the United States, racial and ethnic minorities have higher risk of developing type 2 diabetes (T2D) than Whites. One hypothesis is that some minorities (e.g., Hispanics, Asians) have more visceral fat than Whites in a sex-specific manner. We aimed to test this hypothesis by examining to what degree racial differences in T2D were explained by visceral fat in males and females.
Establishment and Characterization of MCA23, a Novel Mouse Intrahepatic Cholangiocarcinoma Cell Line
α-SMA alpha-smooth muscle actin AFP alpha-fetoprotein Arg1 hepatic cell marker arginase 1 CK7 cytokeratin 7 CK19 cytokeratin 19 CTG cell tracker green EMT epithelial-mesenchymal transition GPC3 glypican 3 H&E hematoxylin and eosin HTVi hydrodynamic tail-vein injection ICC intrahepatic cholangiocarcinoma MDT micro-dissected tumor tissues PI propidium iodide qRT-PCR quantitative real-time polymerase chain reaction STR short tandem repeat TEM transmission electron microscopy TME tumor immune...
Electric-field-driven CO2 polarization and bioinspired proton blocking unlock CO2 reduction in strong acid without metal cations - Nature Communications
Abstract Metal-cation-free CO2 electroreduction (CO2R) in strong acidic media mitigates CO2 reactant losses, eliminates the risk of metal salt precipitation, and broadens device tolerance compared to acidic, neutral, or alkaline system using metal cations. However, such an acidic environment still poses challenges due to the inert and nonpolar nature of CO2 and intensely competitive hydrogen evolution reaction.
Visualization and quantification of lattice strain in battery cathode particles through electron backscatter diffraction imaging - Nature Communications
Abstract Lattice strain critically affects electrochemical performance and durability of battery electrode materials. Here we report an electron-backscatter-diffraction-based imaging method to quantify lattice strain evolution and its spatial heterogeneity in two technologically important layered oxide cathodes (i.e. positive electrodes).
Unravelling gas evolution mechanisms in battery electrode materials - Nature Chemistry
Abstract LiFexMn1−xPO4 positive electrode materials show significant potential for enhancing battery safety, power density and cost-effectiveness. However, gas evolution shortens the cyclability and raises additional safety concerns, presenting a major challenge. The gas evolution mechanisms in LiFexMn1−xPO4 batteries are poorly understood, impeding the material improvement efforts.
Eating duration and shift work are associated with diabetes: a cross-sectional study among US workers
Diabetes remains a significant public health concern. In the US, 14·7 % of the adults in working age have diabetes, and the prevalence has been continuously increasing(1). This growing prevalence is particularly concerning in the workplace, translating into higher healthcare costs for both employees and employers(Reference Parker, Lin and Mahoney2). In 2018, 16 % US workforce had shift work schedule(Reference Woods3).
Topotaxially grown composite cathodes for cobalt-free high-energy long-life Li-ion batteries - Nature Communications
Abstract The vehicle industry’s increasing demand for electrification necessitates the removal of expensive and rare cobalt from current high-energy batteries. However, eliminating cobalt poses challenges due to its vital role in maintaining the layered structural ordering and cycling stability of commonly used Li(NiMnCo)O2 cathodes.
Trilaciclib triggers a neutrophil-related immune response and sensitizes non-small cell lung cancer to anti-PD-1 therapy
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By Yuan Gao Verified, Yuchao He, Chengmeng Wang, Ran Zuo, Yi Luo, Wei Liu, Ping Yue, Wenchen Gong, Yu Wang, Liwei Chen, zhiyong Liu, Peng R. Chen, Hua Guo, Xiangdong Tian, Duo Zuo, Yuanying Feng, Aomei Ling
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Cell Reports Medicine
Verified
Gallium‐Based Liquid Metals as an Engineered Multifunctional Platform: from Biomedical Innovations to Energy and Material Systems
Conflict of Interest The authors declare no conflict of interest. References 1, , , , , Chem. Soc. Rev. 2018, 47, 2518. 2, , , , , , Small 2020, 16, 1903391. 3, , , , , , , , Chem. Mater. 2023, 35, 964. 4, , , , , Nanoscale Horiz. 2024, 9, 1099. 5, , , Ultrason. Sonochem. 2015, 26, 340. 6, , , , , , , , , , , , , , , J. Am. Chem. Soc. 2018, 141, 104. 7, , , Acc. Mater. Res. 2021, 2, 1093. 8, , , , , , , Adv. Mater. 2024, 36, 2406783. 9, , , , , , , , , , , , , Adv. Mater. 2021, 33, 2103062. 10, , , , , , , , Adv. Mater.
Frontiers | Global, regional, and national burden of vitamin A deficiency (1990–2021) and projections to 2042: associations with sociodemographic development
1Department of Rehabilitation Medicine, Shenzhen Bao’an Shiyan People’s Hospital, Bao’an Clinical Institute of Shantou University Medical College, Shenzhen, China 2Department of Traditional Chinese Medicine, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, China Background: Vitamin A deficiency (VAD) remains a significant public health concern. Currently, there is a lack of comprehensive, up-to-date global assessments on the specific burden of VAD.
Enhanced specific energy in fast-charging lithium-ion batteries negative electrodes via Ti-O covalency-mediated low potential - Nature Communications
Abstract Developing lithium-ion batteries with high specific energy and fast-charging capability requires overcoming the potential-capacity trade-off in negative electrodes. Conventional fast-charging materials (e.g., Li4Ti5O12, TiNb2O7) operate at high potentials (>1.5 V vs. Li+/Li) to circumvent lithium plating, yet this compromises specific energy.
Full article: Long working hours related to elevated psychological distress among United States pregnant workers: findings from the National Health Interview Survey
Abstract Long working hours and psychological distress have each been related to adverse maternal health and birth outcomes. Understanding the potential psychological health impacts of long working hours among pregnant workers may support the implementation of maternity work protections in the United States (U.S.).
Endophytic bacteria-assisted cadmium removal in sunflower stalks: towards safe biomass recycling
No potential conflict of interest was reported by the author(s). Data is available on request from the authors. Additional information This work was supported by the Research Foundation of Education Bureau of Hunan Province under [Grant 22B1085] and the Natural Science Foundation of Hunan Province under [Grant 211109415018].
The Bidirectional Relationship Between Subjective Well-Being and Depre
Back to Journals » Psychology Research and Behavior Management » Volume 18 Authors Cao C , Yu G, Chen L, Qin J, Lin Z Received 11 December 2024 Accepted for publication 21 February 2025 Published 21 March 2025 Volume 2025:18 Pages 719—731 DOI https://doi.org/10.2147/PRBM.S508588 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Mei-Chun Cheung Chen Cao,1 Guilan Yu,1 Liwei Chen,2 Jun Qin,3 Zhongyong Lin1...
Optimal power schedule for distributed Kalman filtering under DoS attacks: a Stackelberg game strategy
Abstract This paper investigates the power schedule problem for a cyber-physical system under signal-to-interference-plus-noise ratio (SINR)-based denial-of-service (DoS) attacks. In contrast to the existing works where only a single channel or a multi-channel network with an estimation centre is considered, the interactive dynamic game process in a fully distributed wireless sensor network is concerned in this paper based on a distributed Kalman filtering framework.
Gradient-porous-structured Ni-rich layered oxide cathodes with high specific energy and cycle stability for lithium-ion batteries - Nature Communications
Abstract Ni-rich layered oxides (LiNixCoyMn1−x−yO2, x > 0.8, NCM) are technologically important cathode (i.e., positive electrode) materials for next-generation high-energy batteries. However, they face challenges in cycle stability and durability due to internal strain accumulation and particle fracture as the batteries cycle. Here we report a simple molten-salt-assisted synthesis route to introduce gradiently distributed pores into the polycrystalline NCM secondary particles.
Electronic communications between active sites on individual metallic nanoparticles in catalysis - Nature Communications
Abstract Catalytic activity of metal particles is reported to originate from the appearance of nonmetallic states, but conductive metallic particles, as an electron reservoir, should render electron delivery between reactants more favorably so as to have higher activity. We present that metallic rhodium particle catalysts are highly active in the low-temperature oxidation of carbon monoxide, whereas nonmetallic rhodium clusters or monoatoms on alumina remain catalytically inert.
Two-dimensional crystalline platinum oxide - Nature Materials
Abstract Platinum (Pt) oxides are vital catalysts in numerous reactions, but research indicates that they decompose at high temperatures, limiting their use in high-temperature applications. In this study, we identify a two-dimensional (2D) crystalline Pt oxide with remarkable thermal stability (1,200 K under nitrogen dioxide) using a suite of in situ methods.
A Bandgap‐Tuned Tetragonal Perovskite as Zero‐Strain Anode for Potassium‐Ion Batteries
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Mechanism of Laser‐Induced Self‐Deposition of Nanoparticles Identified by In Situ Observation
1 Introduction Recently, the demand for electric vehicles to replace fueled ones has been increasing owing to the growing problem of carbon dioxide emissions.
Exploring the role of blood pressure in the black-white disparity in cardiovascular disease mortality: a causal mediation analysis
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Exploring the role of blood pressure in the black-white disparity in cardiovascular disease mortality: a causal mediation analysis
Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways. View Full Text Read the full text or download the PDF:
Association of Occupational and Leisure-time Physical Activity with Allostatic Load
Leisure-time physical activity (LTPA) decreases allostatic load (AL), a measure of burden of chronic stress. However, the role of occupational PA (OPA) is unknown. This study examined associations of OPA and LTPA with AL among workers in the United States (US). This cross-sectional study included 6944 US workers aged 20–64 years from the National Health and Nutrition Examination Survey (2007–2018). PA was assessed using the Global Physical Activity Questionnaire.
Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders
Highlights • HFD promotes iron overload in hypothalamic AgRP neurons • AgRP neuron activity is stimulated by iron overload • Iron overload in AgRP neurons causes central insulin and leptin resistance • Oxidative and ER stress in AgRP neurons is regulated by iron Summary Iron overload is closely associated with metabolic dysfunction. However, the role of iron in the hypothalamus remains unclear.
Antimicrobial residues in meat from chickens in Northeast Vietnam: analytical validation and pilot study for sampling optimisation
Article Dans Une Revue Journal für Verbraucherschutz und Lebensmittelsicherheit Année : 2024 Antimicrobial residues in meat from chickens in Northeast Vietnam: analytical validation and pilot study for sampling optimisation Mots clés Poultry market Chicken farm Antibiotic residues Maximal residue limit Withdrawal period LC–MS/MS Fichier principal FournieGuillaume_JournalOfConsumerProtectionAndFoodSafety_2024.pdf (978.73 Ko) Télécharger le fichier Origine : Fichiers éditeurs autorisés sur une...
Metabolomic Biomarkers of Dietary Approaches to Stop Hypertension (DASH) Dietary Patterns in Pregnant Women
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Performance Potential of a Concentrated Photovoltaic-Electrochemical Hybrid System
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Trends and Risk Factors of Diabetes and Prediabetes in US Adolescents, 1999-2020
Abstract To assess the national trends in prevalence of diabetes and prediabetes and their major risk factors among adolescents in the US. We analyzed data on 6,936 adolescents aged 12 to 19 years from the National Health and Nutrition Examination Surveys (NHANES) between 1999 and 2020. Diabetes was defined by self-reported physician-diagnosis (diagnosed) and by fasting plasma glucose and HbA1c levels (undiagnosed). Prediabetes was identified by fasting plasma glucose and HbA1c levels.
Real‐world outcomes of 18,186 metastatic solid tumor outpatients: Baseline blood cell counts correlate with survival after immune checkpoint inhibitor therapy
This study analyzed data collected from an electronic health record database of 18,186 patients. Routine pre-treatment blood test data was assessed for correlation with survival for patients with advanced skin, lung, or kidney tumors receiving treatment that stimulates the person’s immune system to fight cancer. Patient information came from The US Oncology Network community clinics between January 1, 2015 and May 31, 2021. Results showed blood cell count tests corresponded with patient survival.
Adverse drug reactions of non-statin antihyperlipidaemic drugs in China from 1989 to 2019: a national database analysis
CLINICAL PHARMACOLOGY Lipid disorders Adverse events STRENGTHS AND LIMITATIONS OF THIS STUDY The authorised national database was used to analyse the adverse drug reactions (ADRs) of non-statin antihyperlipidaemic drugs in China from 1989 to 2019. The difference in the ADR ratios between fibrates was compared in the Chinese population.
The role and mechanisms of rstA in the intracellular survival of fish pathogenic Aeromonas hydrophila
Abstract In this study, RNAi technology was used to silence the gene rstA in Aeromonas hydrophila. The strain rstA-RNAi displayed significant decrease in intracellular survival compared with that of the wild-type strain B11.
2D Covalent Organic Framework for Water Harvesting with Fast Kinetics and Low Regeneration Temperature
Graphical Abstract Exceptional water adsorption/desorption dynamic properties and low regeneration temperature were achieved by 2D covalent organic frameworks (COFs) with 1D open channels and alternatively arranged hydrophilic/hydrophobic segments. It is promising for improving cycle efficiency and lowering the energy consumption in the atmospheric water harvesting processes. Abstract Atmospheric water harvesting represents a promising technique to address water stress.
Biomarker testing and tissue journey among patients with metastatic non-small cell lung cancer receiving first-line therapy in The US Oncology Network Biomarker testing in metastatic NSCLC with first-line therapy
Highlights • MYLUNG analyzed biomarker testing in metastatic NSCLC in community-based oncology practices. • Median time from diagnosis to 1L treatment initiation was approximately 5 weeks. • Turnaround time from test orders to results availability was approximately 2 weeks. • Only 35% had test results before first-line treatment initiation for all 5 biomarkers. • NGS testing rates increased with time but remained below 50% over the study period.
Metal‐Triazolate‐Framework‐Derived FeN4Cl1 Single‐Atom Catalysts with Hierarchical Porosity for the Oxygen Reduction Reaction
Communication Linyu Hu, Key Laboratory of Cluster Science Ministry of Education, Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion Materials, Advanced Technology Research Institute (Jinan), School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 100081 P. R.
Programmable C:G to G:C genome editing with CRISPR-Cas9-directed base excision repair proteins
Abstract Many genetic diseases are caused by single-nucleotide polymorphisms. Base editors can correct these mutations at single-nucleotide resolution, but until recently, only allowed for transition edits, addressing four out of twelve possible DNA base substitutions. Here, we develop a class of C:G to G:C Base Editors to create single-base genomic transversions in human cells. Our C:G to G:C Base Editors consist of a nickase-Cas9 fused to a cytidine deaminase and base excision repair proteins.
Stressful life events, hypertensive disorders, and high blood sugar during pregnancy
RESEARCH ARTICLE Fan Wang Corresponding Author E-mail address: wangfan75@hotmail.com https://orcid.org/0000-0003-4816-9596 Department of Obstetrics, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China Correspondence Fan Wang, PhD, Department of Obstetrics, The Second Affiliated Hospital of Wenzhou Medical University, Zhejiang, Wenzhou, China.
Risk for Gestational Diabetes Among Asian Women
Abstract and Introduction Abstract Introduction: Asian women have a higher prevalence of gestational diabetes mellitus than women of other races/ethnicities. We aimed to compare the prevalence of gestational diabetes among Asian American women to other racial/ethnic groups and explore whether the higher occurrence of the disorder among Asian women can be explained by acculturation.
Stressful Life events, hypertensive disorders and high blood sugar during pregnancy
RESEARCH ARTICLE Fan Wang Corresponding Author E-mail address: wangfan75@hotmail.com https://orcid.org/0000-0003-4816-9596 Department of Obstetrics, The Second Affiliated Hospital of Wenzhou Medical University, China Correspondence Fan Wang, Ph.D.,Department of Obstetrics, The Second Affiliated Hospital of Wenzhou Medical University,zhejiang, China, Email: wangfan75@hotmail.com, Phone:86‐0577‐88002209.
Reconfiguration of interfacial energy band structure for high-performance inverted structure perovskite solar cells
Abstract Charged defects at the surface of the organic–inorganic perovskite active layer are detrimental to solar cells due to exacerbated charge carrier recombination. Here we show that charged surface defects can be benign after passivation and further exploited for reconfiguration of interfacial energy band structure.
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