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Potentially functional variants of Wnt signaling pathway genes predict risk of primary lung cancer in Chinese Han population
Abstract Wnt signaling is a highly conserved pathway that regulates cell proliferation, differentiation, apoptosis and stem cell self-renewal, which has implications for embryonic development and tumorigenesis. We investigated the potential role of candidate single nucleotide polymorphisms (SNPs) of Wnt signaling pathway genes with computational evidence of regulatory potential on lung cancer in Chinese Han patients.
OACLBES: an opposition-based adaptive chaotic Lévy bald eagle search algorithm
Advanced search Engineering Optimization Latest Articles Submit an article Journal homepage Full Article Figures & data References Supplemental Citations Metrics Reprints & Permissions Read this article /doi/full/10.1080/0305215X.2026.2693123?needAccess=true Abstract The Bald Eagle Search (BES) algorithm is a nature-inspired metaheuristic widely used for complex optimization problems, but it can suffer from premature convergence and limited population diversity.
Bclaf1 drives heart failure by recruiting Srsf2 to enhance Hand2 pre-mRNA splicing and pathological hypertrophy
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Abstract Heart failure with reduced ejection fraction (HFrEF) remains a major therapeutic challenge. B-cell lymphoma 2-associated transcription factor 1 (Bclaf1) is implicated in RNA splicing and cardiac disease, but its role in HFrEF pathogenesis is unknown. Here, we demonstrate that Bclaf1 expression is elevated in human HFrEF myocardium and in male murine pressure-overload models.
By Yang Zhang, Haiyu Gao, Ying Lu, Yingzi Zhang, Xiaofang Zhang, Yinfeng Zhao, Liying Yu, Shuang Wang, Lexin Zhao, Guohui Yang, Jialiang Li, Jiaxin Yu, Chenhong Li, Changzhu Li, Yifan Wang Verified, Ying Yang, YUE LI, Luyang Yu, Deli Zhao, Lida Yang, Lei Jiao, Baofeng Yang, Yanjie Lu, Zhenwei Pan, Yinghe Zhai
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Nature
Verified
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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Liying
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