Brian Gural, Logan Kirkland, Abigail Hockett, Peyton Sandroni, Jiandong Zhang, Manuel Rosa-Garrido, Samantha K. Swift, Douglas J. Chapski, Michael A. Flinn, Caitlin C. O’Meara, Thomas M. Vondriska, Michaela Patterson, Brian C. Jensen, Christoph D. Rau. Abstract Interpreting bulk RNA sequencing from heterogeneous tissues like the post-myocardial infarction (MI) heart is confounded by dynamic changes in cell-type composition.