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Luca Bartesaghi on Muck Rack

Luca Bartesaghi

As seen in: Cell Press
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Articles

Tight Spaces, Tighter Signals: Spatial Constraints as Drivers of Peripheral Myelination

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By Luca Bartesaghi, Basilio Giangreco, Vanessa Chiappini, Martina Monaco
| Preprints.org
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Sh3tc2 deficiency affects neuregulin-1/ErbB signaling

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By Luca Bartesaghi, Fanny Schüpfer, Jean-Jacques Médard, Estelle Arnaud Gouttenoire
| upv.es
[EN] Mutations in SH3TC2 trigger autosomal recessive demyelinating Charcot-Marie-Tooth type 4C (CMT4C) neuropathy. Sh3tc2 is specifically expressed in Schwann cells and is necessary for proper myelination of peripheral ...[+] [EN] Mutations in SH3TC2 trigger autosomal recessive demyelinating Charcot-Marie-Tooth type 4C (CMT4C) neuropathy. Sh3tc2 is specifically expressed in Schwann cells and is necessary for proper myelination of peripheral axons.
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PRDM12 Is Required for Initiation of the Nociceptive Neuron Lineage during Neurogenesis

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By Luca Bartesaghi, Yiqiao Wang, Paula Fontanet
| Cell Press Verified
Highlights • PRDM12 is expressed in neural crest cells (NCCs) and all nociceptive lineage neurons • Inactivation of PRDM12 results in the absence of the entire nociceptive lineage • Forced expression of PRDM12 in NCCs represses non-nociceptor fates • PRDM12 regulates progenitor proliferation and the sensory neurogenesis program Summary The sensation of pain is essential for the preservation of the functional integrity of the body.
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