Lucas A Salas on Muck Rack

Lucas A Salas

Verified
Argentina, Bogota D.C.
As seen in: El Diario 24 Ar, Nature, Wiley Online Library, MDPI, El Tiempo, Genome Biology, Genome Medicine, International Journal of Epidemiology, European Respiratory Journal, Future Medicine, Hecho En California
Premio Nac. de Periodismo Simón Bolivar 🎙🏆 Periodista📺 Ahora: @secnewgate_co Antes: @canalcitytv @eltiempo
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Articles

Endothelial cell-specific DNA methylation alterations in breast cancer

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By Barbara Karakyriakou, Ze Zhang, Hanxu Lu, Lucas A Salas Verified, Brock C. Christensen
| Nature Verified
Abstract DNA methylation alterations are well-established contributors to carcinogenesis, yet, in the tumor microenvironment (TME), patterns of lineage and cell-specific methylation alterations are not well understood. Single-cell DNA methylation profiling in the TME is limited by technical challenges and high costs.
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Integrative epigenetics and transcriptomics identify aging genes in human blood - Nature Communications

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By Kejun Ying, Jesse R. Poganik, Chiara Herzog, Qingwen Chen, Alexander Tyshkovskiy, Alec W. Eames, Ludger J.E. Goeminne, Daniel L. McCartney, Lucas A Salas Verified, Riccardo E Marioni, Jessica Lasky-Su, Michael Snyder, Dmitrii Glubokov, Benyamin Matei-Dediu
| Nature Verified
Abstract Recent epigenome-wide studies have identified a large number of genomic regions that consistently exhibit changes in their methylation status with aging across diverse populations, but the functional consequences of these changes are largely unknown. On the other hand, transcriptomic changes are more easily interpreted than epigenetic alterations, but previously identified age-related gene expression changes have shown limited replicability across populations.
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Reply to: “Comments on the paper ‘Extensive epigenomic dysregulation is a hallmark of homologous recombination deficiency in triple‐negative breast cancer’ by Y. Chen et al.”

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By Youdinghuan Chen, Lucas A Salas Verified, Jonathan D. Marotti, Nicole Jenkins
| Wiley Online Library Verified
Corresponding Author Brock C. Christensen Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Lebanon, New Hampshire, USA Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, New Hampshire, USA Department of Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Lebanon, New Hampshire, USA Correspondence Brock C.
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