Ze Zhang on Muck Rack

Ze Zhang

Québec
As seen in: Color Research & Application, Nature, Wiley Online Library, PLOS ONE, ScienceDirect, Frontiers, Frontiers in Immunology, Gut Journal, MDPI, Taylor & Francis Online and
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Articles

Antioxidant lipid nanoparticles enhance mRNA stability for regeneration therapy and gene editing

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By Benhao Li, Mengyao Zhao, Bowei Yang, Taihua Yang, Yongling Wang, YaXin Hu, Miao Zhang, Jiahao Ge, Xianglong Tang, Ze Zhang, Hengqing Cui, Xiaoyuan Chen, Ling Peng, Qianqian Ni
| Nature
Abstract The success of mRNA vaccines has motivated the development of mRNA therapeutics to treat a wide range of diseases, as well as applications in regenerative medicine. However, the inherent instability of mRNA under conditions of oxidative stress renders these applications challenging. Here we report a general approach to shield mRNA from oxidative degradation by incorporating antioxidant lipid within lipid nanoparticles (LNPs).
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Endothelial cell-specific DNA methylation alterations in breast cancer

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By Barbara Karakyriakou, Ze Zhang, Hanxu Lu, Lucas A Salas , Brock C. Christensen
| Nature
Abstract DNA methylation alterations are well-established contributors to carcinogenesis, yet, in the tumor microenvironment (TME), patterns of lineage and cell-specific methylation alterations are not well understood. Single-cell DNA methylation profiling in the TME is limited by technical challenges and high costs.
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Mutating Methanogens to Enhance Methane Production in Microbial Electrosynthesis Click to copy article link Article link copied!

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By Zhuo Chen, Rongxin Xia, Ze Zhang
| dx.doi.org
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