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Mark A LaBarge on Muck Rack

Mark A LaBarge

As seen in: Nature, MDPI, Cell Press, City of Hope, Chemistry World
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Articles

The breakome of BRCA1 and BRCA2 pathway mutation carriers reveals early processes in breast oncogenesis - Cell Death & Disease

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By Mark A LaBarge, Yotam Drier
| Nature Verified
Abstract DNA double-strand breaks (DSBs) can lead to genomic instability in cancer. Cells rely on an efficient DNA damage response (DDR) to maintain their DNA integrity and prevent oncogenic transformation. However, the early events that connect recurrent DNA damage to oncogenesis are not yet fully understood.
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CYR61 Expression Is Induced by IGF1 and Promotes the Proliferation of Prostate Cancer Cells Through the PI3/AKT Signaling Pathway

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By Greisha L. Ortiz-Hernandez, Stefan Hinz, Mark A LaBarge, Carmina Patrick
| preprints.org
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Mark LaBarge, Ph.D.

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By Mark A LaBarge
| City of Hope
Dr. LaBarge's team specializes in developing human cell systems for understanding why aging is a major risk factor for breast cancer. The objectives of his research program are to generate a comprehensive understanding of the micro-environmental and tissue-level changes in breast that arise with age, and then develop a functional understanding of how those changes: alter mammary gland homeostasis, contribute to breast tumor genesis, and modulate activity of therapeutics.
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