Mark McGregor on Muck Rack

Mark McGregor

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  • Digital News Editor, BBC
Manchester
As seen in: BBC, LinkedIn, Forbes, Nature, TechRadar, The Lancet, Dayton Daily News, Springfield News-Sun, Martech Series, WardsAuto, EMS World and
Digital News Editor @ BBC News.
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Articles

A phase 1 study to assess the safety, tolerability and effectiveness of PV-10 (Rose Bengal Sodium) in neuroendocrine tumours metastatic to the liver - British Journal of Cancer

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By Timothy J Price, Mark McGregor , Laura Depauw, Gabrielle Cehic, Anas Alawawdeh
| Nature
Abstract Metastatic neuroendocrine neoplasms (mNEN) require new treatment options. Intralesional (IL) PV-10 is an autolytic chemotherapy that may elicit an adaptive immune response. This phase 1 study evaluated IL PV-10 administered percutaneously to hepatic lesions in patients with progressive mNEN. IL PV-10 was injected in a single lesion per treatment cycle. A treatment cycle could be repeated after ≥ 6 weeks if multiple targetable lesions were present. The primary endpoint was safety.
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Dual αV-integrin and neuropilin-1 targeting peptide CEND-1 plus nab-paclitaxel and gemcitabine for the treatment of metastatic pancreatic ductal adenocarcinoma: a first-in-human, open-label, multicentre, phase 1 study

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By Andrew Dean, Sanjeev Gill, Mark McGregor , Vy Broadbridge
| The Lancet
Background CEND-1 is a novel cyclic peptide that targets αV integrins and neuropilin-1 and enhances tumour delivery of co-administered anticancer drugs. We investigated the safety, tolerability, and biological activity of CEND-1 in patients with metastatic pancreatic ductal adenocarcinoma in combination with nab-paclitaxel and gemcitabine.
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2022 Priceville High School Graduation Photos - The Hartselle Enquirer

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By Mark McGregor 
| Hartselle Enquirer
Tuesday, May 17, 2022 8:51 am East Highland Baptist Church, 1030 Main Street E, will hold a special 6-week study on creation facilitated by Mike Loudiana, PhD physicist, on Wednesday evenings ... Read more |
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