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Marta García-León

As seen in: Cell Press, Cell Reports
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Articles

Cross-species interactome analysis uncovers a conserved selective autophagy mechanism for protein quality control in plants

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By Marintia M. Nava-García, Anita Bianchi, Marion Clavel, Ranjith K. Papareddy, Lina Benchalel, Veselin I. Andreev, Varsha Mathur, Azadeh Mohseni, Marta García-León, Peng Gao, Lorenzo Picchianti, Nenad Grujic, Roksolana Kobylinska, Alibek Abdrakhmanov, Heloise Duverge, Gaurav Anand, Nils Leibrock, Juncai Ma, Margot Raffeiner, Timothy Crawford, Luca Argirò, Mateusz Matuszkiewicz, Jakob Valdbjørn Kanne, Anton Meinhart, Elisabeth Roitinger, Isabel Bäurle, Byung Kang, Morten A Petersen, Suayib Üstün, Yogesh Kulathu, Tim Clausen, Silvia Ramundo, Yasin F Dagdas, Cheuk-Ling Wun
| Cell Press Verified
Keywords selective autophagy selective autophagy receptor proteostasis ATG8 aggrephagy protein aggregate heat stress autophagic flux receptor evolution proteotoxic stress Introduction Macroautophagy (hereafter autophagy) is essential for maintaining organismal homeostasis amid fluctuating environmental conditions.1 It recycles damaged or unnecessary macromolecules and organelles, facilitating cellular renewal and adaptation.2 Autophagy enables organisms to withstand a wide spectrum of abiotic...
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Hormone-mediated disassembly and inactivation of a plant E3 ubiquitin ligase complex

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By Cristina Martinez, Cristina Martínez Verified, Campus de Cantoblanco, Elisa Iniesto, Marta García-León
| Cell Reports Verified
Keywords ABA signaling ABA receptor CRL4 E3 ligases CSN CSN5 inhibitor DDA1 PYL8 PYR/PYL/RCAR Arabidopsis plant proteostasis Research topic(s) CP: Plants CP: Molecular biology Introduction Targeted destabilization of proteins by the ubiquitin-proteasome system (UPS) regulates key developmental and stress responses in plants, including their adaptation to abscisic acid (ABA)-mediated abiotic stresses, such as drought, high salinity, and low temperatures.1,2,3 ABA signaling is triggered by the...
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