Skip To Main Content
Max Ulibarri on Muck Rack

Max Ulibarri

As seen in: BioRxiv, Cell Reports
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Max

Contact Max, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Epithelial organoid supports resident memory CD8 T cell differentiation

|
By Max Ulibarri, Ying Lin, Geongoo Han, Julian C. Ramprashad
| Cell Reports Verified
Highlights • Vaginal epithelial stem cells form organoids mimicking in vivo vaginal epithelium • CD8 T cells co-cultured with organoids differentiate into resident memory CD8 T cells • In vitro CD8 TRMs phenotypically and transcriptionally resemble in vivo epithelial TRMs • VEO-CD8 co-culture model can be interrogated to reveal fundamental TRM biology Summary Resident memory T cells (TRMs) play a vital role in regional immune defense.
Open in Who Shared Issue with article?

Epithelial organoid supports resident memory CD8 T cell differentiation

|
By Ying Lin, Geongoo Han, Max Ulibarri, Julian R Ramprashad
| BioRxiv
Abstract Resident Memory T cells (TRM) play a vital role in regional immune defense in barrier organs. Although laboratory rodents have been extensively used to study fundamental TRM biology, poor isolation efficiency, sampling bias and low cell survival rates have limited our ability to conduct TRM-focused high-throughput assays. Here, we engineered a murine vaginal epithelial organoid (VEO)-CD8 T cell coculture system that supports CD8 TRM differentiation in vitro.
Open in Who Shared Issue with article?
See all 2 articles