Maya Lotan-Pompan

Keywords preterm infants microbiome antibiotic antibiotic resistance Research topic(s) CP: Microbiology Introduction Preterm birth, defined as childbirth at less than 259 days or 37 completed weeks of gestation, is the leading cause of perinatal morbidity and mortality in developed countries and the second leading cause of death in children under the age of five worldwide.1 The prevalence of preterm birth has been increasing in most countries, ranging from approximately 5% in some European...

Table S3 of this manuscript as originally published accidentally displayed the non-normalized RFS values for p53 protein variants. This has been corrected in the online supplemental information, which now displays the RFS values after normalization, performed as described under Computational Analysis in STAR Methods. This correction has no impact on the conclusions drawn from this table (the correlation between the originally published and the corrected values is 0.993).

Massively Parallel Measurement of the Functional Impact of p53 Mutations The Functional Impact of Distinct p53 Mutations Correlates with Protein Structural Domains and Evolutionary Conservation Residues within the DBD exhibit differential robustness to modification Mutation Prevalence in Human Tumors Is Correlated with Loss of Anti-proliferative Capacity p53 Mutations that Disrupt WT-like Functionality In Vitro Span a Broad Phenotypic Spectrum In Vivo and May Exhibit Selective GOF Models for...