Megan Kuhn on Muck Rack

Megan Kuhn

Washington, D.C.
As seen in: HuffPost, Cell Press, Flight International, The Journal of Clinical Investigation, Times-Mail
Flight International reporter, wanderlust
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Articles

Resident tissue macrophages maintain intraocular pressure homeostasis

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By Katy C. Liu, Aleksander Grimsrud, María Suárez Verified, Darren Schuman, Michael L. De Ieso, Megan Kuhn, Ruth Kelly, Rose Mathew, Joan Kalnitsky, Matthias Mack, Gerasimos Anagnostopoulos, Florent Ginhoux, Violet Bupp-Chickering, Revathi Balasubramanian, Simon John, W. Daniel Stamer, Daniel Saban
| Cell Press Verified
Keywords glaucoma macrophages monocytes mononuclear phagocytes ontogeny intraocular pressure trabecular meshwork Get full text access Log in, subscribe or purchase for full access. References 1. Quigley, H.A. ∙ Broman, A.T. The number of people with glaucoma worldwide in 2010 and 2020 Br. J. Ophthalmol. 2006; 90:262-267 2. Heijl, A. ∙ Leske, M.C. ∙ Bengtsson, B.
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Intracameral Puncture Lowers Intraocular Pressure and Triggers an Immune Response in the Conventional Outflow Tract

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By Darren Schuman, María Suárez Verified, Aleksander Grimsrud, Megan Kuhn
| biorxiv.org
Abstract Purpose: Intracameral injection is an effective delivery method for biomedical agents and therapeutics to conventional outflow tract tissues. However, the effect of intracameral injections on intraocular pressure and aqueous dynamics has not been well characterized, warranting further investigation. Methods: Wild type 3-5-month-old C57BL/6 mice were subjected to intracameral puncture (ICP, without injection of any material).
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Endothelial-specific postnatal deletion of Nos3 preserves intraocular pressure homeostasis via macrophage recruitment and NOS2 upregulation

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By Ruth Kelly, Megan Kuhn, Revathi Balasubramanian, Ester Reina-Torres
| The Journal of Clinical Investigation
ResearchImmunologyOphthalmologyVascular biology Open Access | 10.1172/JCI183440 J Clin Invest. https://doi.org/10.1172/JCI183440. Copyright © 2025, Kelly et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. View PDF Abstract Polymorphisms in Nos3 increases risk for glaucoma, the leading cause of irreversible blindness worldwide.
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