Metabolic Disorders
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Medicinal mushrooms and type 2 diabetes: mechanistic insights, translational evidence, and clinical caveats
Abstract Type 2 diabetes mellitus (T2DM) is a highly prevalent and rapidly expanding global metabolic disorder. Medicinal mushrooms have recently been proposed as promising functional foods, owing to their broad range of bioactive compounds, including β-glucans and other polysaccharides, triterpenoids, phenolic metabolites, sterols, nucleoside analogs, and sulfur-containing antioxidants.
Proteostasis in the regulation of pancreatic islet cell plasticity
INTRODUCTION Pancreatic islet cells are highly specialized secretory cells that continuously synthesize and secrete large amounts of peptide hormones, including insulin and glucagon, in response to metabolic demands1. This secretory activity places a substantial burden on the endoplasmic reticulum (ER), which requires tightly coordinated proteostasis to maintain cellular homeostasis. Consequently, pancreatic islet cells rely on efficient proteostasis to preserve their function and viability.
Biomarker Technologies Global Market Report 2026
Biomarker technologies refer to tools and analytical approaches used to identify and quantify biological markers within the body to understand health conditions and disease progression. These technologies analyze biological samples such as blood, tissue, urine, and saliva through genomics, proteomics, metabolomics, and molecular diagnostics methods. They help detect specific indicators associated with diseases, treatment effectiveness, and physiological changes.
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