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Articles by Michael Ebner
Graz: Sturm scheitert im Cup an Austria Lustenau
Sturm verpasst den Aufstieg Für den SK Sturm Graz ist der Weg im ÖFB-Cup beendet. Die Grazer unterlagen am Donnerstag bei Austria Lustenau mit 2:3 und mussten damit im Achtelfinale die Segel streichen. Die Vorarlberger nutzten ihre Möglichkeiten konsequenter und feierten den ersten Sieg ihrer Vereinsgeschichte gegen Sturm. Die Partie begann aus Grazer Sicht mit einer frühen Warnung.
Sturm reagiert auf Khudyakov-Aus: Adam Stejskal als neue Torhüter-Option
Sturm Graz holt erfahrenen Keeper Der SK Sturm Graz hat auf die schwere Verletzung von Daniil Khudyakov reagiert und mit Adam Stejskal einen neuen Torhüter verpflichtet. Der 24-jährige Tscheche wechselt mit sofortiger Wirkung zu den "Schwoazn" und soll die Grazer Torhüterriege für die restliche Saison verstärken. Stejskal bringt Bundesliga-Erfahrung mit: In den vergangenen drei Saisonen absolvierte er für die WSG Tirol insgesamt 95 Bundesliga-Partien.
Built a recruiter and dashboard with ChatGPT Work to find jobs that fit my skills and work history
5D AGO I've had many conversations with ChatGPT about my job search, resume tailoring, and cover letter writing. It knows a lot about my experience and which jobs might be a good fit, so I decided to have ChatGPT Work search for opportunities instead of spending time searching job boards myself.
Control of lysosome function by the GTPase-activating protein TBC1D9B and its binding partner TMEM55B
Abstract Lysosomes are highly dynamic organelles that serve antagonistic functions as terminal catabolic stations for the degradation of macromolecules and as central metabolic decision centers for anabolic growth signaling. Lysosome dysfunction is implicated in various human diseases. The physiological roles of lysosomes are linked to the control of lysosome position and dynamics via the activity of the kinesin-activating small GTPase ARL8.
Nutrient-regulated control of lysosome function by signaling lipid conversion
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Main text (Cell 186, 5328–5346.e1–e12; November 22, 2023) In the originally published version of this article, we noted two errors: Figure S2D erroneously showed the same graph as in Figure 1C. The error was introduced by the authors when replacing the low-resolution graphs used during the review process with high-resolution editable versions for final publication.
By Michael Ebner, Dmytro Puchkov, Orestes López-Ortega, Pathma Muthukottiappan, Yanwei Su, Christopher Schmied, Gillian L. Dornan, Max T. Lucht, Wonyul Jang, Philipp Koch, Alexander Wallroth, Martin Lehmann, Britta Brügger, Mario Pende, Dominic Winter, Volker Haucke, Silke Zillmann, Iryna Nikonenko, Jochen Koddebusch, Vonda Koka
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Cell Press
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After FDR won 4 elections, Americans soured on presidents serving more than two terms
Amid the abundance of controversies evoked by the presidencies of Donald Trump, I am anticipating legal scholars will opine vis-a-vis the 22nd Amendment to the U.S. Constitution — the two-term limit — ratified in 1951. Trump, so it appears upon reading early tea leaves, apparently has entertained the impulse to contrive a path to upend this constitutional artifice, in place for 74 years. It is my understanding that President Franklin D.
International press welcomed to London Institute for Healthcare Engineering
Press visit explores LIHE's ambition to deliver MedTech innovation at pace. On Wednesday 5th June 2024, the London Institute for Healthcare Engineering (LIHE) hosted guests from the international press to discuss the future of medical device entrepreneurship and commercialisation. LIHE’s director, Professor Sebastien Ourselin, welcomed journalists to the new building and explained its role as a dedicated space for MedTech entrepreneurs and King’s healthcare industry partners.
Nutrient-regulated control of lysosome function by signaling lipid conversion
Highlights • Starvation promotes lysosomal catabolism via local PI(4)P synthesis on lysosomes • Cells harbor distinct populations of lysosomes marked by PI(3)P and PI(4)P • A nutrient-regulated lipid switch triggers interconversion of lysosome populations • mTORC1 signaling and lysosomal PI(4)P synthesis interdependently repress each other Summary Lysosomes serve dual antagonistic functions in cells by mediating anabolic growth signaling and the catabolic turnover of macromolecules.
Community-developed checklists for publishing images and image analyses - Nature Methods
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Abstract Images document scientific discoveries and are prevalent in modern biomedical research. Microscopy imaging in particular is currently undergoing rapid technological advancements. However, for scientists wishing to publish obtained images and image-analysis results, there are currently no unified guidelines for best practices. Consequently, microscopy images and image data in publications may be unclear or difficult to interpret.
By Christopher Schmied, Michael Nelson, Sergiy Avilov, Gert-Jan Bakker, Cristina Bertocchi, Johanna Bischof, Ulrike Boehm, Jan Brocher, Mariana Carvalho, Jana Christopher, Beth Cimini, Eduardo Conde-Sousa, Michael Ebner, Rupert Ecker, Kevin W. Eliceiri, Julia Fernandez-Rodriguez, Nathalie Gaudreault, Laurent Gelman, David Grunwald, Tingting Gu, Nadia Halidi, Mathias Hammer, Matthew Hartley, Marie Held, Florian Jug, Ayse Koksoy, Judith Lacoste, Sylvia Le Dévédec, Sylvie Le Guyader, Gabriel Martins, Aastha Mathur, Kota Miura, Paula Montero Llopis, Adam C. Parslow, Alex Payne-Dwyer, Laure Plantard, Ryan Scott, Arne Seitz, Olaf Selchow, Ved P. Sharma, Martin Spitaler, Sathya Srinivasan, Caterina Strambio-De-Castillia, Douglas Taatjes, Christian Tischer
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Nature
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OrgaMapper: A robust and easy-to-use workflow for analyzing organelle positioning
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
King's College London spin-out Hypervision Surgical Computer Vision Technology features NVIDIA technology to augment surgery study
In a first-time collaboration between NVIDIA and spinout company from the School of Biomedical Engineering & Imaging Sciences, pioneering computer vision technology has been used in an-vivo surgery study at IHU Strasbourg, France, to provide tissue-analytics information previously invisible to the human eye. It is the first time NVIDIA technology has been used in surgery.
The union started ‘parting bonds’ before Lincoln was elected
Abraham Lincoln, upon gaining the American presidency in 1860, eventually convinced himself that he would not get a second term. It was a time of embittered and protracted sectional rivalries that eventually took form as the Civil War.
Biomedical Engineering spinout Hypervision Surgical graduates from prestigious programme
Only 1 of 8 companies graduated from the programme Spinout from King’s School of Biomedical Engineering & Imaging Sciences Hypervision Surgical has graduated from the 2021-2022 Health stream of the Creative Destruction Lab (CDL) programme as 1 of only 8 companies. It was also selected as the single company to represent CDL-Oxford in the CDL Super Session on 23 June 2022.
Guest viewpoint: Leveraging renewables in the new environment
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Julie Devonshire OBE appointed King's Director for King's College London spin-out Hypervision Surgical
Ms Devonshire will represent King’s on the Hypervision Surgical board King’s College London spin out Hypervision Surgical has appointed Julie Devonshire, Director of the Entrepreneurship Institute, as its King’s Director. Ms Devonshire, who has a distinguished career as an entrepreneur herself, will represent King’s on the Hypervision Surgical board, guiding strategic decisions to boost the growth of the company.
Our family’s history reflects Ukraine’s long struggle for peace Original
Refugees, mainly women and children, arrive at Przemysl, Poland on a train from Odesa in Ukraine on Mar. 28. Jeff J. Mitchell/Getty Our grandson, during his customary Sunday evening phone call, recently brought up our family’s legacy vis-à-vis the horrific circumstances unfolding upon Ukraine. Years ago, I had related to him what my grandfather long ago had recounted for me. Our grandson, Jared Ebner, obviously had absorbed it.
Inositol triphosphate-triggered calcium release from the endoplasmic reticulum induces lysosome biogenesis via TFEB/TFE3
In this study, we identify an mTORC1-, ERK-, and PKC-independent pathway for the regulation of lysosome biogenesis via IP 3 -induced calcium release from ER stores downstream of receptor signaling. Multiple lines of evidence support this scenario.
There was a time in history when Republican senators were willing to censure a colleague
On Dec 2, 1954 — 67 years ago this week — Republican members of the U.S. Senate voted to censure their colleague Joseph R. McCarthy of Wisconsin. Taking this step, they aligned with 67 of the Senate’s Democrats. Their issue had to do with the repeated breaches of conduct by Sen. Joseph McCarthy — himself a Republican — recklessly traveling along a fraught path.
NIHR i4i product development award received for novel imaging system
The system will make brain tumour removal surgery safer and more complete A consortium of researchers, clinicians, and industry partners have received an NIHR invention for innovation (i4i) product development award to support a clinical neurosurgery study and quality management system led product development for an intraoperative hyperspectral imaging (HSI) technology, designed to make brain tumour removal surgery safer and more complete.
Real-time surgical hyperspectral imaging system for safe tissue removal undergoes clinical feasibility study
This clinical feasibility case study was published in a special issue of Journal of Physics D: Applied Physics. Its results demonstrate that the research system seamlessly integrates into an operating workflow, with minimal disruption to surgery. The clinical feasibility case study was conducted with a patient undergoing a spinal surgery. An ex vivo study was also performed.
The Chicago Tribune needs a savior
The Chicago Tribune, published since 1847, is navigating perilous financial straits. Indisputably the ascent of digital technology has exerted an irreversible role in the transformation of print journalism in the 21st century. The perils confronting daily newspapers are calculated in unending multiples.
Vannevar Bush: Franklin D. Roosevelt’s Indispensable Expert
by Michael H. Ebner Michael H. Ebner is professor of American history, emeritus, at Lake Forest College. Vannevar Bush with President Harry Truman, 1948 Present-day contempt for scientific expertise takes us back, some eight decades ago, to the Second World War. Enter Vannevar Bush, president of the Carnegie Foundation, who gained a welcomed audience with President Franklin D. Roosevelt.
Mechanical signals regulate TORC2 activity
Maintaining plasma membrane tension is important for eukaryotic cells. How altered membrane tension is sensed and relayed to downstream factors, such as the target of rapamyin complex 2 (TORC2), is poorly understood. Reorganization of a signalling lipid into discrete membrane domains is now shown to inactivate TORC2 in yeast.
lake bluff mulls short term rental laws
LAKE BLUFF — A pair of proposed ordinances dealing with short-term rental of real estate in Lake Bluff are getting refined before further consideration by the Village Board of Trustees. The trustees and Village President Kathy O’Hara asked village attorney Peter Friedman and Administrator Drew Irvin to rework some details of the proposed ordinances during a meeting of the board’s Committee of the Whole February 26 at Village Hall.
lake forest special counsel issues report on amtrak lobbying
LAKE FOREST — A special counsel hired to investigate payments of approximately $200,000 by the city to a Washington D.C. lobbying firm without Lake Forest City Council knowledge found violations of city law but did not recommend termination for officials involved.
How Fascists Took Over Italy with Widespread, Intensely Personal Acts of Political Violence
Before this “takeoff” in provincial fascism, the Fascists were initially an urban phenomenon, motivated primarily by nationalism. They desired revenge against the Socialists and others who had not supported Italy’s participation in the Great War.
How Fascists Took Over Italy with Widespread, Intensely Personal Acts of Political Violence
Fascism A short history of the political violence that helped Mussolini attain power. The Action Team of Lucca in 1922. Jose Antonio/Wikimedia Commons Excerpted fromOrdinary Violence in Mussolini’s Italyby Michael R. Ebner. Published by Cambridge University Press. This article supplements Fascism, a Slate Academy. To learn more and to enroll, visit Slate.com/Fascism.
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