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Articles by Michael McLellan
Publisher Correction: Adjuvant personalized multivalent neoantigen DNA vaccination for MGMT unmethylated glioblastoma: a phase 1 trial
Correction to: Nature Cancer https://doi.org/10.1038/s43018-026-01163-w, published online 12 May 2026. In the version of the article initially published, in the top-left graph of Fig. 3b, the y-axis label was “CD4+CD69+ (%, delta)” but should have been “CD8+CD69+ (%, delta)”. In the top-right box of Fig. 5d, the label “Post-GNOS-PV01” should have read “Pre-GNOS-PV01”. These corrections have been made to the HTML and PDF versions of the article.
Adjuvant personalized multivalent neoantigen DNA vaccination for MGMT unmethylated glioblastoma: a phase 1 trial
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Abstract Glioblastoma is a fatal disease with a median prognosis of 12–18 months. Recent studies have shown encouraging results using neoantigen-based vaccines to stimulate glioblastoma-directed immune responses, but overall immunogenicity has been low.
By Elizabeth A. R. Garfinkle, Renzo Perales-Linares, Ryan C Gimple, Alexandra J. Livingstone, Kaleigh Roberts, Omar Butt, S. Peter Goedegebuure, Michael McLellan, Gue Su Chang, Jasreet Hundal, Jian Yan, Jaye B. Navarro, Sophia A. Paxton, Srestha Chattopadhyay, Neil Cooch, Alfredo Perales-Puchalt, Konstantina Stavroulaki, Sarah Rochestie, Joann Peters, Beth Junker, Jian L. Campian, Milan G. Chheda, Michael R. Chicoine, Albert Kim, Jon Willie, Gregory J. Zipfel, Joshua Dowling Verified, Christopher Miller Verified, Obi L. Griffith, Malachi Griffith, William E. Gillanders, Katherine Miller Verified, Elaine R. Mardis, Niranjan Y. Sardesai, Gavin P. Dunn, Tanner Johanns
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Nature
Verified
Author Correction: Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy - Nature Medicine
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Correction to: Nature Medicine https://doi.org/10.1038/s41591-022-01696-4, published online 3 March 2022. In the version of this article initially published, the name of the Edward P. Evans Foundation was shown incorrectly in the first sentence of the Acknowledgements. The name has been corrected in the HTML and PDF versions of the paper.
By Irene Ganan-Gomez, Feiyang Ma, Kelly S. Chien, Ganiraju Manyam, Caleb A. Class, Rashmi Kanagal-Shamanna, Sanam Loghavi, Sarah Schneider, Vera Adema, Michael McLellan, Nicola Giuliani, Matteo Pellegrini, Jing L. Wang, Jason Renard Walker, Ziyi Li, Koichi Takahashi, Michael Andreeff, Simona Colla, Muharrem Muftuoglu
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Nature
Verified
Hania Aguilar: Michael McLellan arrested in kidnapping and murder of 13-year-old Lumberton girl
The FBI and Lumberton police have made an arrest in the kidnapping and murder of 13-year-old Hania Noelia Aguilar. Michael Ray McLellan, 34, is charged with first-degree murder, first-degree forcible rape, statutory rape of a person under 15 years of age or younger, first-degree sexual offense, statutory sex offense with a person 15 years or younger, first-degree kidnapping, felony larceny, felony restraint, abduction of child and concealment of a death.
Hania Aguilar: Michael Ray McLellan arrested in kidnapping and murder of 13-year-old girl
The FBI and Lumberton police have made an arrest in the kidnapping and murder of 13-year-old Hania Noelia Aguilar. Michael Ray McLellan, 34, is charged with first-degree murder, first-degree forcible rape, statutory rape of a person under 15 years of age or younger, first-degree sexual offense, statutory sex offense with a person 15 years or younger, first-degree kidnapping, felony larceny, felony restraint, abduction of child and concealment of a death.
Hania Aguilar: Michael Ray McLellan arrested in kidnapping and murder of 13-year-old North Carolina girl
LUMBERTON, North Carolina -- The FBI and Lumberton police have made an arrest in the kidnapping and murder of 13-year-old Hania Noelia Aguilar. Michael Ray McLellan, 34, is charged with first-degree murder, first-degree forcible rape, statutory rape of a person under 15 years of age or younger, first-degree sexual offense, statutory sex offense with a person 15 years or younger, first-degree kidnapping, felony larceny, felony restraint, abduction of child and concealment of a death.
Hania Aguilar: Michael Ray McLellan arrested in kidnapping and murder of 13-year-old Lumberton girl
The FBI and Lumberton police have made an arrest in the kidnapping and murder of 13-year-old Hania Noelia Aguilar. Michael Ray McLellan, 34, is charged with first-degree murder, first-degree forcible rape, statutory rape of a person under 15 years of age or younger, first-degree sexual offense, statutory sex offense with a person 15 years or younger, first-degree kidnapping, felony larceny, felony restraint, abduction of child and concealment of a death.
Michael Ray McLellan: Suspect charged in kidnapping, murder of 13-year-old North Carolina girl Hania Aguilar
The FBI and Lumberton police have made an arrest in the kidnapping and murder of 13-year-old Hania Noelia Aguilar. Michael Ray McLellan, 34, is charged with first-degree murder, first-degree forcible rape, statutory rape of a person under 15 years of age or younger, first-degree sexual offense, statutory sex offense with a person 15 years or younger, first-degree kidnapping, felony larceny, felony restraint, abduction of child and concealment of a death.
Suspect charged in kidnapping, murder of 13-year-old North Carolina girl
NORTH CAROLINA -- The FBI and Lumberton police have made an arrest in the kidnapping and murder of 13-year-old Hania Noelia Aguilar. Michael Ray McLellan, 34, is charged with first-degree murder, first-degree forcible rape, statutory rape of a person under 15 years of age or younger, first-degree sexual offense, statutory sex offense with a person 15 years or younger, first-degree kidnapping, felony larceny, felony restraint, abduction of child and concealment of a death.
Hania Aguilar: Michael Ray McLellan arrested in kidnapping and murder of 13-year-old Lumberton girl
The FBI and Lumberton police have made an arrest in the kidnapping and murder of 13-year-old Hania Noelia Aguilar. Michael Ray McLellan, 34, is charged with first-degree murder, first-degree forcible rape, statutory rape of a person under 15 years of age or younger, first-degree sexual offense, statutory sex offense with a person 15 years or younger, first-degree kidnapping, felony larceny, felony restraint, abduction of child and concealment of a death.
Suspect charged in kidnapping, murder of 13-year-old North Carolina girl Hania Noelia Aguilar
NORTH CAROLINA -- The FBI and Lumberton police have made an arrest in the kidnapping and murder of 13-year-old Hania Noelia Aguilar. Michael Ray McLellan, 34, is charged with first-degree murder, first-degree forcible rape, statutory rape of a person under 15 years of age or younger, first-degree sexual offense, statutory sex offense with a person 15 years or younger, first-degree kidnapping, felony larceny, felony restraint, abduction of child and concealment of a death.
Technology Fuels Domino's Pizza Resurgence -
Domino’s Pizza is back. The chain’s same-store sales went up 12.2% in the fourth quarter of 2016. That number was tops in the US restaurant business for that period. For the most part, the final three months of 2016 were not kind to restaurant operators. Factors such as low grocery prices, bad weather, and decreased retail traffic negatively impacted many restaurant companies’ quarterly earnings. One secret to the resurgence of Domino’s could be its technology.
Will Twitter's Data Gold Mine Ever Fully Pay Off? -
Twitter has become a key communication platform as major events unfold live in real-time around the world. Large news and media companies such as the BBC, CNN, and the New York Times regularly use the service to distribute and promote content, while Twitter also allows even the most remote or isolated individuals to get their message out. CMOs and sales leaders use it. Twitter went public in 2013, raising about $1.82 billion in the process. But 2016 was not kind to the company.
US Media Companies Hit Roadblocks in China
Television and movies are wildly popular American exports. Yet many American media and entertainment companies continue to get the cold shoulder from the Chinese government, which is notorious for controlling all forms of media its citizens consume. Despite the enormous consumer market potential in China, US-based media companies are finding it difficult, if not impossible, to find success in the Chinese market. Disney and Apple have had their movie services shuttered in China.
Inside the Marriott-Starwood Hotels Merger
EU regulators recently approved the $12+ billion hotel company mega merger between Marriott International and Starwood Hotels & Resorts Worldwide. The merger will create the world’s biggest hotel company with more than 5,500 hotels and about 1.1 million rooms in some 100 countries worldwide. The transaction should gain final regulatory approval in the US soon and the headline-grabbing deal will likely close shortly thereafter.
How Does Facebook Maintain Its Staggering Growth?
No wonder the powers that be recently added a “love” option for Facebook users — the good news just keeps coming in for the social media behemoth. The company’s stock price has spiked in the past two weeks on the strength of better-than-expected quarterly earnings and sales figures. Facebook has experienced exponential growth over the past few years, enabling it to dominate the social networking world as the most-trafficked site of its kind.
How CMOs Use Twitter
Today’s CMOs need to stay hip to the digital world and marketing trends that change constantly. Many top CMOs have embraced social media as an effective means to connect with peers and keep up with rapidly-evolving industry best practices. Social media agency Leadtail recently released a report that breaks down the Twitter activity of more than 1,050 CMOs in January 2016.
McDonald’s is Cashing in on Breakfast, But Challenges Remain
Last week McDonald’s posted its best quarterly sales growth in nearly four years after making its popular breakfast items available all day, a move that could help the company finally turn the tide. The long-time king of the fast-food industry has struggled in recent years as consumers move toward healthy foods, different morning options, or what they perceive as higher quality burgers and fries. Breakfast has become a huge part the revenue picture for many fast-food restaurant enterprises.
How CIOs Use Twitter
Modern day CIOs need to stay informed about the constantly changing information and technology landscape. Many top CIOs are embracing social media as a way to connect with peers and stay current on industry best practices. Social media agency Leadtail recently released a report that breaks down the Twitter activity of more than 400 North American CIOs in December 2015.
How Sales Leaders Use Twitter
How are companies using social media to drive sales? Is Twitter a waste of time for salespeople? What topics are sales leaders interested in sharing and retweeting? What brands do they interact with most often through tweets? Social media agency Leadtail recently released a report on how sales leaders are using Twitter that reveals some of the possible answers to questions that companies are constantly asking themselves (and rightly so).
Chipotle Closings Highlight Supply Chain Risks
Chipotle Mexican Grill is a leader in the fast casual restaurant space. The chain has enjoyed rapid expansion over the past several years, opening nearly 200 new locations every year. In an effort to maintain control over food quality, Chipotle does not rely on franchising as part of its growth strategy.
Can Cloud Software Freshen Up Whole Foods?
It’s been a bumpy ride in recent weeks for some pretty big-time brands. Groupon and Twitter both announced significant layoffs, while Netflix has seen its stock price nosedive. Wal-Mart’s stock took a tumble yesterday after the retail powerhouse announced fairly bleak earnings projections. Meanwhile, once-booming Austin-based Whole Foods Market is turning to cloud-based retail software as the grocery chain tries to get things moving in the right direction again after a series of struggles.
How Mobile Apps are Transforming the Travel Industry
It’s hard to remember what it was like to book a flight or a find an appropriate hotel before the Internet made it so doggone easy for travelers to look at flight schedules, prices, and pictures of hotel accommodations online. But technology isn’t done transforming the global travel experience just yet. In fact technology, social media, and mobile apps are making nearly every aspect of travel easier to manage than ever before.
Relativity Media, Lions Gate Illustrate Film Industry Volatility
The movie business has not suffered as badly as the music and television industries in the digital age. However, Hollywood studios are not printing money the way they once were. The high-stakes financing that goes into feature-film production remains a very risky business. A legitimate hit movie or a box office bomb can make or break a company’s future.
Biotech Companies Lead Recent IPO Wave
In case you didn’t already know – health care is big business. A large percentage of companies going through the initial public offering (IPO) process in the past few weeks are focused on health.
How Hilton's Diversity Helps It Dominate the Hotel Business
Companies operating in the travel, lodging, leisure, and hospitality industries have their ups and downs. Competition is fierce and unending, while labor costs and upkeep on properties are expensive. Operating in an unpredictable industry, Hilton Worldwide has maintained steady revenue growth for the past five fiscal years. In fiscal 2014, its revenue was $10.5 billion. That was an increase of 8% compared to fiscal 2013.
Chinese Companies Surge in Global Rankings
Apparently the economy in China is still booming. The country’s economic prosperity has helped Chinese firms further invade the Financial Times’ FT Global 500 list. A total of 20 Chinese firms that were not previously on the list joined the party, while not a single Chinese company dropped off the list in 2015. The FT Global 500 list is an annual ranking of the world’s largest companies. The companies are ranked by market capitalization, which is basically the stock market value of a company.
Why Restaurant IPOs Keep Coming Freaky Fast
The latest trend in the fast-casual restaurant business is going public. A heaping helping of restaurant companies have served up fresh IPOs in recent months, including the high profile Shake Shack sweepstakes, which raised $150 million back in January. This week Wingstop’s IPO raised more than $110 million. Wingstop follows the $147 million May IPO of Southern-style chicken-and-biscuit chain Bojangles.
Is Fast Food King McDonald’s In Trouble?
McDonald’s added almost 1,000 locations worldwide during 2014, with an emphasis on European and Asian markets. But now the Golden Arches is closing hundreds of its stores as its sales continue to sag. The chain plans to slash costs by closing about 220 under-performing restaurants located primarily in the US and China, along with 130 restaurants in Japan. In fiscal 2014 the company’s European segment accounted for about 40% of revenue, while the US accounted for nearly a third.
Why Casinos are Struggling to Contain Costs
Most gamblers and casual observers assume casinos make money hand over fist. But even with billions in revenue, some large gaming companies are suffering net losses as a result of the high cost of doing business. Boyd Gaming operates more than 20 gaming entertainment properties, including several Las Vegas-area casino hotels. Boyd reported $2.7 billion in revenue for fiscal 2014, down from $2.89 billion the previous year.
Panera Bread Keeps Its Food Fresh and Revenue Rising
Panera Bread Company has grown from serving about 60 customers per day at its first bakery-cafe to serving almost 8 million customers per week system-wide. The company is a leader in the quick-casual restaurant business, with more than $2.5 billion in annual sales and about 1,880 bakery-cafes located throughout the US and Ontario, Canada. Most of the company’s bakery-cafes are located in urban, suburban, strip mall, and regional mall locations.
Kraft-Heinz Merger Creates US Food Titan
Some makers of processed foods are shuttering plants as global consumers’ tastes shift to fresh and whole foods. But this week’s historic $46 billion megamerger of two iconic American processed food makers, H.J. Heinz and Kraft Foods, means heaping helpings of all-American ketchup, hotdogs, processed cheese, and an entire grocery basket full of popular convenience foods will all be manufactured by one big US company.
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