Michal Dudek on Muck Rack

Michal Dudek

United Kingdom
As seen in: Nature, Annals of the Rheumatic Diseases, European Research Studies
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Articles

Author Correction: Macromolecular condensation buffers intracellular water potential - Nature

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By Lara K. Krüger, Kerrie E. McNally, Vicente Jose Planelles-Herrero, Michal Dudek, Silvia Barbiero, Sew Yeu Peak-Chew, Benjamin T. Porebski, Nina M Rzechorzek, Andrew Beale, Jörg Morf, Jan Brugués, Joseph Chambers, Qing-Jun Meng, John S. O’Neill, John O’neill, Rachel S. Edgar
| Nature Verified
Correction to: Nature https://doi.org/10.1038/s41586-023-06626-z Published online 18 October 2023 In the version of the article initially published, –Ψπ /RT (mOsm kg–1) originally appeared as –Ψπ (mOsm kg–1) in Figs. 1a, 4b and c, 5b, c and d and Extended Data Figs. 1, 4 and 10. Also, osmolality was originally labelled as osmotic potential in Fig. 5b and Extended Data Fig. 10, and osmolarity was originally labelled as osmolality in Extended Data Fig. 8.
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Modulation of circadian rhythms in articular cartilage by heat pulses

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By Cátia Gonçalves, Michal Dudek, Dharshika Pathiranage, Anna Paszek
| biorxiv.org
Abstract Objective: Prior studies have shown that disruption of the circadian clock leads to cartilage degeneration in mice while shift work is associated with higher risk of osteoarthritis (OA) in humans. In this study we investigated the potential of heat pulses to restore dampened circadian rhythms in articular cartilage. Methods: Femoral head cartilage explants and primary chondrocytes were isolated from PER2::LUC mice.
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Mechanical loading and hyperosmolarity as a daily resetting cue for skeletal circadian clocks - Nature Communications

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By Michal Dudek, Beatriz Bano-Otalora, Craig Lawless, Liu Yang, Farshid Guilak, Judith Hoyland
| Nature Verified
Abstract Daily rhythms in mammalian behaviour and physiology are generated by a multi-oscillator circadian system entrained through environmental cues (e.g. light and feeding). The presence of tissue niche-dependent physiological time cues has been proposed, allowing tissues the ability of circadian phase adjustment based on local signals. However, to date, such stimuli have remained elusive.
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