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Mikhail A. Kostylev on Muck Rack

Mikhail A. Kostylev

As seen in: Nature, MDPI, ACS Publications, Cell Press, Physical Review B, The Journal of Biological Chemistry
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Articles

Distinct Filament Conformation for Receptor-Bound Amyloid-β from Alzheimer’s Disease Brain

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By Mikhail A. Kostylev, Graham Roseman, Yangyi Liu, Tanina Arab, Ruibing Wu, Pallavi P Gopal, Stephen M. Strittmatter, Carmen Butan
| Nature Verified
Abstract Alzheimer’s disease is triggered by amyloid-β, with symptoms linked to synapse loss. Oligomeric amyloid-β, rather than monomeric or fibrillar amyloid-β, has been proposed to be the proximate mechanistic cause, but the relevant molecular characteristics have remained unclear. To define the biologically relevant species, we isolated a receptor-bound amyloid-β pool from Alzheimer’s disease brain by release with a receptor antagonist and purification to homogeneity.
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Controlled Capture of Magnetic Nanoparticles from Microfluidic Flows by Ferromagnetic Antidot and Dot Nanostructures

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By Reyne Dowling, Mikhail A. Kostylev
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Cellular Prion Protein Conformational Shift after Liquid–Liquid Phase Separation Regulated by a Polymeric Antagonist and Mutations

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By Yangyi Liu, Marcus D. Tuttle, Mikhail A. Kostylev, Graham Roseman
| ACS Publications
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