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Articles by Ming Cui
Identification of serum 5’tRF-Val as a promising non-invasive biomarker for early detection of esophageal cancer
Abstract Esophageal cancer (EC) is frequently detected at an advanced stage because of the lack of effective noninvasive screening tools, leading to poor prognosis. This study aimed to identify serum transfer RNA-derived small RNA (tsRNA) biomarkers for early detection of EC. Candidate tsRNAs were screened using the tsRFun database, and a quantitative real-time PCR (qRT‒PCR) method for serum 5’tRF-Val was subsequently established and validated.
A phase II peri-operative study of pembrolizumab plus lenvatinib for mucosal melanoma
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Abstract Mucosal melanoma is an aggressive malignancy with limited neoadjuvant options. We conducted a single arm, phase II study of neoadjuvant pembrolizumab plus lenvatinib followed by surgery and adjuvant pembrolizumab in resectable mucosal melanoma (NCT04622566) along with exploratory biomarker analysis.
By Lili Mao, Yumei Lai, Hong Zheng, Ming Cui, Lifeng Li, Ziyi Liu, Hongyu Zhou, Linzi Sun, Caili Li, Xiaoting Wei, Xue Bai, Yan Kong, Chuanliang Cui, Zhihong Chi, Xinan Sheng, Bin Lian, Siming Li, Xieqiao Yan, Bixia Tang, Juan Li, Li Zhou Verified, Xuan Wang, Jun Guo, Jie Dai, Lu Si
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Nature
Verified
A Novel FXR-Targeted DUBTAC and Its Applications in Cholestasis Therapy Click to copy article link Article link copied!
Cite Jump to ExpandCollapse ArticleMarch 20, 2026 A Novel FXR-Targeted DUBTAC and Its Applications in Cholestasis Therapy Click to copy article linkArticle link copied! Ming Cui Ming Cui State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210000, P. R. China Jiangsu Provincial Key Laboratory of Targetome and Innovative Drugs, Institute of Innovative Drug Discovery and Development, China Pharmaceutical University, Nanjing 210000, P. R.
Spatial transcriptomics defines the molecular progression, invasion and immune landscape of IPMN and IPMN-derived pancreatic cancer
Spatial transcriptomics defines the molecular progression, invasion and immune landscape of IPMN and IPMN-derived pancreatic cancer Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Targeting metabolic-epigenetic-immune axis in cancer: molecular mechanisms and therapeutic implications - Signal Transduction and Targeted Therapy
Abstract Cancer cells orchestrate a highly dynamic and interconnected network spanning metabolic, epigenetic, and immune mechanisms to drive adaptive plasticity and continuous development. This review synthesizes emerging insights into the coevolutionary strategies employed by malignant and stromal cells—particularly tumor cells and immune populations—across the continuum of tumorigenesis, metastasis, and treatment resistance.
The Longitudinal and Reciprocal Associations Among Maternal Aggravation, Verbal Aggression, and Internalizing Problems from Childhood to Adolescence
This version is not peer-reviewed. Submitted: 11 December 2025 You are already at the latest version Parents have major influences on child wellbeing, including the development of inter-nalizing symptomology in their children. Furthermore, the emotional impact between parents and their children could be reciprocal.
Developing a Highly Reducing Heterogeneous Nickel Photocatalyst with Photoexcited Hantzsch Esters
Cite Jump to ExpandCollapse ArticleSeptember 1, 2025 Developing a Highly Reducing Heterogeneous Nickel Photocatalyst with Photoexcited Hantzsch Esters Click to copy article linkArticle link copied! Ming Cui Ming Cui Department of Chemistry, The University of Hong Kong, Hong Kong 999077, China State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Hong Kong 999077, China Deyang Wang Deyang Wang Department of Chemistry, The University of Hong Kong, Hong Kong 999077, China Jun...
Racial Stress, Social Support, and Racial Socialization Among Rural Black Mothers: Associations With Preschoolers' Executive Functioning
1 Introduction Racial stress is defined as the psychological and physiological strain that individuals experience because of racism and racial discrimination. It arises when people encounter or anticipate racially charged experiences that challenge their sense of safety, identity, or well-being (Harrell 2000).
Study on the Spatiotemporal Heterogeneity and Threshold Effects of Ecosystem Services in Honghe Prefecture, Yunnan Province
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Longitudinal Dyadic Associations Between Maternal Monitoring, Household Environment and Mother-Adolescent Closeness
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement Research data are not shared. References , , and . 2024. “Affective Dynamics in Mother-Adolescent Dyads: Links to Mental Health and Relationship Quality.” Cognition and Emotion 38, no. 4: 654–660. https://doi.org/10.1080/02699931.2024.2316835. , , , and . 2021. “Examining the Effects of Household Chaos on Child Executive Functions: A Meta-Analysis.” Psychological Bulletin 147, no. 1: 16–32.
Enhancing Electron Donor–Acceptor Complex Photoactivation with a Stable Perylene Diimide Metal–Organic Framework
Introduction Click to copy section linkSection link copied! Due to their high tunability and expanded photoredox potentials, organo-photocatalysts have recently been widely explored in photoinduced organic transformations.
Enhancing Electron Donor–Acceptor Complex Photoactivation with a Stable Perylene Diimide Metal–Organic Framework
Introduction Click to copy section linkSection link copied! Due to their high tunability and expanded photoredox potentials, organo-photocatalysts have recently been widely explored in photoinduced organic transformations.
Treating myocardial infarction via a nano-ultrasonic contrast agent-mediated high-efficiency drug delivery system targeting macrophages
Research Article APPLIED SCIENCES AND ENGINEERING INTRODUCTION Ischemic heart disease remains a leading cause of mortality and disability worldwide, affecting approximately 126 million people globally (1, 2). Myocardial infarction (MI) is the most severe form of ischemic heart disease (3). Now, adverse ventricular remodeling and heart failure following MI continue to be the primary contributors to patient mortality (4).
Indulgent Parenting and Adolescents’ Maladjustments: The Roles of Cultural Context and Parental Gender
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Overparenting and romantic relationships in emerging adulthood: Roles of relationship efficacy and parent-child relationship quality
Objective Guided by the theory of emerging adulthood and social cognitive theory, we investigated whether overparenting was associated with romantic relationship quality among emerging adults through relationship efficacy and dependent on parent–child relationship quality. Background Establishing healthy and lasting intimate relationships is one of the primary developmental tasks during emerging adulthood.
Medical Complexity of Children with Special Healthcare Needs and Healthcare Experiences
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Discrepancies in Perceived Indulgent Parenting, Relationship Satisfaction, and Psychological Well-Being of Adolescents and Parents
1. Introduction Adolescence is a critical developmental stage when many changes happen, which could be challenging for both adolescents and their parents. As children become adolescents, they face changes brought on by the process of puberty, increasing academic demands, and growing social pressure. Lerner and Steinberg [1] suggest that these challenges, though accompanied by opportunities, could lead to psychological well-being problems among adolescents.
Sustainability | Free Full-Text | Spatiotemporal Patterns and Drivers of Trade-Offs and Synergy in the Beijing-Tianjin Sand Source Control Project: A Bayesian Belief Network-Based Analysis
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Cyst fluid glycoproteins accurately distinguishing malignancies of pancreatic cystic neoplasm - Signal Transduction and Targeted Therapy
Abstract Pancreatic cystic neoplasms (PCNs) are recognized as precursor lesions of pancreatic cancer, with a marked increase in prevalence. Early detection of malignant PCNs is crucial for improving prognosis; however, current diagnostic methods are insufficient for accurately identifying malignant PCNs. Here, we utilized mass spectrometry (MS)-based glycosite- and glycoform-specific glycoproteomics, combined with proteomics, to explore potential cyst fluid diagnostic biomarkers for PCN.
Overexpression of ferroptosis-related genes FSP1 and CISD1 is related to prognosis and tumor immune infiltration in gastric cancer
Jiayi Zang [1] ; Ming Cui [1] ; Lin Xiao [1] ; Jianzhong Zhang [2] ; Rongrong Jing [1] [1] Department of Laboratory Medicine, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China [2] Department of Laboratory Medicine, Affiliated Rudong Hospital of Nantong University, Nantong, 226001, China Localización: Clinical & translational oncology, ISSN 1699-048X, Vol. 25, Nº. 8 (August), 2023, págs.
Indulgent Parenting and the Psychological Well-Being of Adolescents and Their Parents
Abstract : Adolescence is a time for identity development and exploration. Indulgent parenting during adolescence could be developmentally inappropriate and could be associated with adolescent psychological well-being problems. Little research on indulgent parenting, however, has included and investigated both adolescent and parental well-being problems.
Patterns of indulgent parenting and adolescents' psychological development
Objective In this study, researchers aimed to extend the current literature by examining the patterns of indulgent parenting of both mothers and fathers and their associations with adolescents' basic psychological needs satisfaction, self-control, and self-efficacy. Background Indulgent parenting could be harmful for the development of psychological needs satisfaction and cognitive abilities when adolescents seek autonomy and gain emotional regulatory skills.
Overparenting and psychological well‐being of emerging adult children in the United States and China
Objective This study aimed to investigate (a) the association between overparenting and emerging-adult children's psychological maladjustment through basic psychological needs satisfaction (autonomy, competence, and relatedness) and (b) whether the associations, particularly the associations between overparenting and needs satisfaction, vary by cultures. Background Research in Western countries suggests that overparenting may undermine emerging-adult children's psychological well-being.
Copper‐Catalyzed Highly Enantioselective Addition of a Silicon Nucleophile to 3‐Substituted 2H‐Azirines Using an Si−B Reagent
Dedicated to Professor Douglas W. Stephan on the occasion of his 70th birthday Graphical Abstract The first catalytic asymmetric synthesis of C-silylated, unprotected aziridines has been accomplished. Using a silyl boronic ester as a latent silicon nucleophile, a chiral copper catalyst enables its addition of 3-substituted 2H-azirines in high yields and with excellent enantioselectivities.
Parent-Child Communication, Relationship Quality, and Female Young Adult Children’s Well-Being in U.S. and Finland
Purchase/rental options available: Buy Article for $40.00 (USD) Abstract: Parent-child communication and parent-child relationship quality could influence young adult children’s well-being. Further, the associations between parent-child communication and relationship quality and young adult children’s well-being could differ in various cultural environments.
Parent-Child Communication, Relationship Quality, and Female Young Adult Children’s Well-Being in U.S. and Finland
Parent-child communication and parent-child relationship quality could influence young adult children’s well-being. Further, the associations between parent-child communication and relationship quality and young adult children’s well-being could differ in various cultural environments. In this study, we examined the associations among these constructs and potential cultural differences with two large samples of female college students from the U.S. (N = 393) and Finland (N = 264).
Necrolytic migratory erythema: an important sign of glucagonoma
Necrolytic migratory erythema: an important sign of glucagonoma http://orcid.org/0000-0001-8770-4585Ming Cui1, Ruojun Wang2, Quan Liao1 1 Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China 2 Department of Dermatology, Peking University First Hospital, Beijing, China Correspondence to Professor Quan Liao, Department of General Surgery, Peking Union Medical College Hospital, Beijing 100730,...
Interface engineering of transitional metal sulfide-MoS2 heterostructure composites as effective electrocatalysts for water-splitting
Interface engineering of transitional metal sulfide–MoS2 heterostructure composites as effective electrocatalysts for water-splitting Yanqiang Li, *a Zehao Yin,†a Ming Cui,a Xuan Liu,a Jiabin Xiong,b Siru Chen†*b and Tingli Ma *cd Author affiliations * Corresponding authors a State Key Laboratory of Fine Chemicals, School of Petroleum and Chemical Engineering, Dalian University of Technology, Panjin Campus, Panjin 124221, China E-mail: yanqiangli@dlut.edu.cn b Center for Advanced Materials...
Interface engineering of transitional metal sulfides-MoS2 heterostructure composites as effective electrocatalysts for water-splitting
Interface engineering of transitional metal sulfides-MoS2 heterostructure composites as effective electrocatalysts for water-splitting Siru Chen, Zehao Yin, Ming Cui, Xuan Liu, Jia-Bin Xiong, Yanqiang Li and Tingli Ma Abstract Benefiting from the high electrochemical surface area brought by 2D nanosheet structure, MoS2 has received great research attention for hydrogen evolution reaction (HER).
Single‐Atom and Dual‐Atom Electrocatalysts Derived from Metal Organic Frameworks: Current Progress and Perspectives
Review Ming Cui State Key Laboratory of Fine Chemicals, School of Petroleum and Chemical Engineering, Dalian University of Technology, Panjin Campus, Panjin, 124221 P. R. China These authors contributed equally to this work. Search for more papers by this author Prof. Liwei Mi Corresponding Author mlwzzu@163.com Henan Key Laboratory of Functional Salt Materials, Center for Advanced Materials Research, Zhongyuan University of Technology, Zhengzhou, 450007 P. R.
Metal organic frameworks based bifunctional oxygen electrocatalysts for rechargeable zinc-air batteries: current progress and perspectives
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Necrolytic migratory erythema: an important sign of glucagonoma
Necrolytic migratory erythema: an important sign of glucagonoma http://orcid.org/0000-0001-8770-4585Ming Cui1, Ruojun Wang2, Quan Liao1 1Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China 2Department of Dermatology, Peking University First Hospital, Beijing, China Correspondence to Professor Quan Liao, Department of General Surgery, Peking Union Medical College Hospital, Beijing 100730,...
A Novel Marker in Parathyroid Carcinoma
close Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. Log out Cancel In This Article Abstract and Introduction Abstract Objective: A differential diagnosis between malignant and benign parathyroid lesions is difficult due to their overlapping clinicopathological characteristics. As such, molecular markers are urgently needed.
Portal Venous Gas
A 72-year-old man presented to the emergency department with an 11-hour history of periumbilical abdominal pain and inability to pass flatus. His medical history included chronic lymphocytic leukemia (for which he had been taking ibrutinib), type 2 diabetes, and chronic hepatitis B virus infection. The pulse was 155 beats per minute, and the blood pressure 83/52 mm Hg. On physical examination, his abdomen was diffusely tender, with the most severe pain in the right upper quadrant.
Helicopter Parenting and Young Adults’ Well-Being: A Comparison Between United States and Finland
ABC News . (2007). Helicopter parents hover over kids’ lives. Retrieved from http://abcnews.go.com/GMA/story?id=3699441 Google Scholar ABC News . (2009). “Helicopter moms”: Hurting or helping your kids? Retrieved from http://abcnews.go.com/2020/Parenting/story?id=8418453 Google Scholar Bandura, A. (1977). Social learning theory. Englewood Cliffs, NJ: Prentice Hall. Google Scholar Baumrind, D. (1967). Child care practices anteceding three patterns of preschool behavior.
Tumor size classification of the 8<sup>th</sup> edition of TNM staging system is superior to that of the 7<sup>th</sup> edition in predicting the survival outcome of pancreatic cancer patients after radical resection and adjuvant chemotherapy
Since the 1st edition of the TNM staging system was published in 1977, the AJCC/UICC has released a total of eight editions. During the last 40 years, considerable improvements have been achieved in many malignancies, such as melanoma, gastric cancer, colorectal cancer, breast cancer and lung cancer. However, despite tremendous efforts, a diagnosis of PDAC remains devastating15,16,17,18. There has not been any change in the TNM staging system for PDAC in the last three editions.
Cohabiting parents’ marriage plans and marriage realization
The purpose of this study is to examine how cohabiting partners’ plans to marry after the birth of their child were associated with marriage realization or continued cohabitation when their child was 1, 3, and 5 years old. Possible parents’ gender differences, couple agreement, and the longitudinal associations were examined.
Palladium-Catalyzed Sonogashira Coupling of Amides: Access to Ynones via C-N Bond Cleavage
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Homophobia: An Impulsive Attraction to the Same Sex? Evidence From Eye-Tracking Data in a Picture-Viewing Task
Homophobia is typically defined as any negative thoughts, attitudes, or behaviors toward homosexuals as well as an aversion or a fear toward interacting with gay individuals.1, 2, 3, 4, 5 As such, homophobia includes both cognitive and emotional responses toward homosexuality.
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