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Mingzhi Pan

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Articles

Microbiota-metabolome interplay in depression: Metabolic insights and diagnostic potential

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By Mingliang Zhao, Penghong Liu, Yuhuai Guo, Tao Lin Sun, Zhenxing Ren, Xiaojiao Zheng, Mengci Li, Xiaowen Chao, Jijun Wang, Jiahui Zeng, Xiaohua Liu, Yong Yang, Peiyang Luo, Dan Zheng, Junliang Kuang, Keke Ding, Aihua Zhao, Kun Ge, Yingjun OuYang, Guoxiang Xie, Ping Liu, Chuang Wang, Tianlu Chen, TianHong Zhang, tianhong zhang, Ning Sun, Wei Jia, Mingzhi Pan
| Cell Reports Medicine Verified
Keywords microbiota metabolism depression correlations mediation analysis machine learning Introduction Depression presents a substantial burden on both individuals and society, with an increasing prevalence.1,2 Current diagnostic methods rely heavily on clinical interviews and scale scores like the Hamilton Depression Scale (HAMD)-17 test3 and the Patient Health Questionnaire-9 depression module.4 However, patients’ reluctance to disclose their true state and subjective evaluations by...
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