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Mitsukuni Yoshida on Muck Rack

Mitsukuni Yoshida

As seen in: Cell Reports, Cell Press
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Articles

Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice

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By Mitsukuni Yoshida, Jonathan Lin, Akiko Satoh
| Cell Press Verified
Highlights • Circulating levels of eNAMPT decline with age in both mice and humans • Increasing eNAMPT promotes NAD +, counteracts aging, and extends healthspan in mice • eNAMPT is contained exclusively in extracellular vesicles (EVs) in mice and humans • Supplementing eNAMPT in EVs improves physical activity and extends lifespan in mice Summary Aging is a significant risk factor for impaired tissue functions and chronic diseases.
Open in Who Shared Issue with article?
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By Jonathan Lin, Norimitsu Ban, Andrea Santeford, Abdoulaye Sene, Jun Yoshino, Shin-ichiro Imai, Rajendra S. Apte, Shunsuke Kubota, Mitsukuni Yoshida, Rei Nakamura, Nicole Zapata, Miyuki Kubota, Kazuo Tsubota
| secure.jbs.elsevierhealth.com
Open in Who Shared Issue with article?
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