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Mo Cheng

  • Editor, YouMobile, Inc
Verona
As seen in: Nature, Wiley Online Library, Cell Reports Medicine
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Articles by Mo Cheng

Patient-derived vascularized organoid-on-a-chip model for therapeutic response assessment in synovial sarcoma

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By Feili Lo Yang, Hongqiang Zhang, Jiapeng Zhao, Xueqiang Liu, Zhonghang Wang, Xianglin Hu, Mo Cheng, Tu Hu, Zhongze Gu, Wangjun Yan, Zaozao Chen, Wending Huang, Weile Cai
| Nature Verified
Abstract Synovial sarcoma (SS) lacks effective therapies and physiologically relevant models that faithfully recapitulate the tumor microenvironment. Here, we established synovial sarcoma patient-derived organoids (SPDOs) that preserved the histological, genomic, and transcriptomic features of their parental tumors.
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Sintilimab plus Bevacizumab biosimilar IBI305 and chemotherapy as a first-line treatment in advanced gastric or gastroesophageal junction adenocarcinoma (SBAGA): a single-arm, phase Ib/II study

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By Mo Cheng, Pengfei Zhang, Qiancheng Hu, Jitao Zhou, Ruihong Dai, Wenke Li, Jing Wei, Menghui Xu, Yanna Lei, Xiaoying Li, Xiufeng Zheng, Qian Huang, Zhiping Li, Bo Zhang, Wen Zhuang, Zhixin Chen, Xiaolong Chen, Chaoyong Shen, Weihan Zhang, Kai Liu, Linyong Zhao, Xiaonan Yin, Zhaolun Cai, Yuan Yin, Ji Chen, Chunjuan Liu, Deying Kang, Mojin Wang, Hongfeng Gou, Kun Yang, Jiankun Hu, Feng Bi, Ming Liu Verified, Boqiang Peng
| Nature Verified
Abstract Adding anti-PD-1 or anti-VEGF therapy to chemotherapy improves survival in patients with advanced gastric cancer, yet outcomes remain poor. This Phase Ib/II trial aimed to evaluate the efficacy and safety of combining sintilimab, the bevacizumab biosimilar IBI305, and CapeOX chemotherapy as a first-line treatment for patients with HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma (GA/GEJA).
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The association of combined metabolic score for insulin resistance and frailty index with incident cardiometabolic multimorbidity

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By Yang Peng, Lu Zhang, Ping Zhao, Pu Xiang, Mo Cheng, Bi-min Zhu, Bi-bo You
| Nature Verified
Abstract Cardiometabolic multimorbidity (CMM), defined as the coexistence of two or more cardiometabolic diseases, poses a growing global health burden. However, few studies have jointly evaluated the risk of CMM using indicators of both insulin resistance and frailty.
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A pan-cancer single-cell transcriptomic atlas of human bone metastases

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By Shuoer Wang, Fen Ma, Dongliang Wang, Qian Yu, Haoyu Zheng, Ziqing Chen, Songjiao Zhao, Lun Xu, Qingrong Ye, Yiwen Tan, Wending Huang, Zhengwang Sun, Zhiqiang Wu, Meng Fang, Mo Cheng, Yingzheng Ji, Yunkui Zhang, Bingxin Gu, Shaoli Song, Yang Chen, Jiwei Zhang, Yang Shao, Wangjun Yan, Yidi Sun, Weiluo Cai
| Cell Reports Medicine Verified
Keywords bone metastasis single-cell transcriptome atlas pan-cancer immunotherapy Introduction Bone metastases (BMs) are the most common types of bone tumors in adults. It is estimated that 65%–80% of individuals with breast or prostate cancer,1 along with 30%–60% of those with thyroid, kidney, lung, or gastrointestinal cancers,2,3 will experience BM.
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Scalable Synthesis of High‐quality Ultrathin Ferroelectric Magnesium Molybdenum Oxide

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By Xingxing Zhang, Mo Cheng, Qianqian Yang, Jiuxiang Dai
| Wiley Online Library Verified
The development of ultrathin, stable ferroelectric materials is crucial for advancing high-density, low-power electronic devices. Nonetheless, ultrathin ferroelectric materials are rare due to the critical size effect. Here, we present a novel ferroelectric material, magnesium molybdenum oxide (Mg2Mo3O8). High-quality ultrathin Mg2Mo3O8 crystals have been synthesized using chemical vapor deposition. Ultrathin Mg2Mo3O8 has a wide bandgap (∼4.4 eV) and nonlinear optical response.
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Phase‐Modulated Elastic Properties of 2D Magnetic FeTe: Hexagonal and Tetragonal Polymorphs

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By Yunfei Yu, Mo Cheng, Zicheng Tao, Wuxiao Han
| Wiley Online Library Verified
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202308357-sup-0001-SuppMat.pdf641.1 KB Supporting Information References 1, , , , , Nat. Nanotechnol. 2012, 7, 699. 2, , , Nature 2019, 567, 323. 3, , Science 2019, 363, eaav4450. 4, , , Nanoscale Horiz. 2019, 11, 13181. 5, , , , , , , , Appl. Nanosci. 2021, 11, 1075. 6, , , , , , , , , , , , , Nat. Commun. 2014, 5, 5259. 7, , , , , , , , , , , , , , , ACS Nano 2015, 9, 2677.
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