Molly Javier Uyeda on Muck Rack

Molly Javier Uyeda

As seen in: Nature, The Journal of Allergy & Clinical Immunology
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Articles

AML/T cell interactomics uncover correlates of patient outcomes and the key role of ICAM1 in T cell killing of AML - Leukemia

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By Ece Canan Sayitoglu, Allison Boss, Molly Javier Uyeda, Yusuke Nakauchi, Norman J. Lacayo, Ravindra Majeti, Andrew J. Gentles, Alma-Martina Cepika
| Nature Verified
Abstract T cells are important for the control of acute myeloid leukemia (AML), a common and often deadly malignancy. We observed that some AML patient samples are resistant to killing by human-engineered cytotoxic CD4+ T cells. Single-cell RNA-seq of primary AML samples and CD4+ T cells before and after their interaction uncovered transcriptional programs that correlate with AML sensitivity or resistance to CD4+ T cell killing.
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Tregopathies: Monogenic diseases resulting in regulatory T-cell deficiency

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By Alma-Martina Cepika, Yohei Sato, Jeffrey Liu, Molly Javier Uyeda
| The Journal of Allergy & Clinical Immunology Verified
Tregopathies: Monogenic diseases resulting in regulatory T-cell deficiency , , , Molly Javier Uyeda x Molly Javier Uyeda Search for articles by this author Affiliations Department of Pediatrics, Division of Stem Cell Transplantation and Regenerative Medicine, Stanford School of Medicine, Stanford, Calif Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford, Calif , BS , Rosa Bacchetta x Rosa Bacchetta Search for articles by this author...
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